Vessel bioengineering

Circulation Journal : Official Journal of the Japanese Circulation Society
Shuhei TaraToshiharu Shinoka

Abstract

The development of vascular bioengineering has led to a variety of novel treatment strategies for patients with cardiovascular disease. Notably, combining biodegradable scaffolds with autologous cell seeding to create tissue-engineered vascular grafts (TEVG) allows for in situ formation of organized neovascular tissue and we have demonstrated the clinical viability of this technique in patients with congenital heart defects. The role of the scaffold is to provide a temporary 3-dimensional structure for cells, but applying TEVG strategy to the arterial system requires scaffolds that can also endure arterial pressure. Both biodegradable synthetic polymers and extracellular matrix-based natural materials can be used to generate arterial scaffolds that satisfy these requirements. Furthermore, the role of specific cell types in tissue remodeling is crucial and as a result many different cell sources, from matured somatic cells to stem cells, are now used in a variety of arterial TEVG techniques. However, despite great progress in the field over the past decade, clinical effectiveness of small-diameter arterial TEVG (<6mm) has remained elusive. To achieve successful translation of this complex multidisciplinary technology to the clin...Continue Reading

References

Jul 1, 1992·Circulation·UNKNOWN VA Coronary Artery Bypass Surgery Cooperative Study Group
Jul 5, 1990·The New England Journal of Medicine·J R VaneR M Botting
Jul 1, 1995·Journal of Biomedical Materials Research·M C HilesR J Morff
Apr 1, 1995·The Journal of Surgical Research·G E SanduskyS F Badylak
Nov 1, 1994·Current Opinion in Cardiology·M G Bourassa
May 14, 1993·Science·R Langer, J P Vacanti
Jan 1, 1996·Nature Medicine·Y NoishikiA Matsumoto
Jan 23, 1998·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·M S Conte
Dec 5, 1998·Science·J Gearhart
Apr 16, 1999·Science·L E NiklasonR Langer
Feb 28, 2001·The New England Journal of Medicine·T Shin'okaY Ikada
Jun 5, 2001·The Annals of Thoracic Surgery·J G MeinhartP Zilla
Apr 18, 2003·Biomaterials·Goki MatsumuraToshiharu Shin'oka
Jun 28, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·P SimonE Wolner
Oct 16, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Daniel D SwartzStelios T Andreadis
Nov 2, 2005·Tissue Engineering·Gordon M RihaChangyi Chen
Feb 24, 2006·Nature Medicine·Nicolas L'HeureuxTodd N McAllister
May 26, 2007·Biomaterials·Stephen F Badylak
Jul 7, 2007·Proceedings of the National Academy of Sciences of the United States of America·Craig K HashiSong Li
Dec 15, 2007·Nature Protocols·Kazutoshi TakahashiShinya Yamanaka
Sep 12, 2008·Tissue Engineering. Part a·Seung-Woo ChoByung-Soo Kim
Jun 16, 2009·Journal of Pediatric Surgery·Tamar L MirenskyChristopher K Breuer
Jul 9, 2009·Physiological Reviews·Jessica E Wagenseil, Robert P Mecham
Dec 4, 2009·Journal of Vascular Surgery·Soichiro EnomotoMasataka Sata
Dec 19, 2009·Regenerative Medicine·Swathi Ravi, Elliot L Chaikof
Jan 29, 2010·The Journal of Thoracic and Cardiovascular Surgery·Narutoshi HibinoToshiharu Shinoka
Mar 9, 2010·Proceedings of the National Academy of Sciences of the United States of America·Jason D RohChristopher K Breuer
Mar 23, 2010·Biomaterials·Sabine KochStefan Jockenhoevel
Jan 5, 2011·Organogenesis·Kristine C RustadGeoffrey C Gurtner
Mar 23, 2011·Journal of Biomaterials Science. Polymer Edition·Yan SuSeeram Ramakrishn

❮ Previous
Next ❯

Citations

Oct 3, 2015·Biochemical and Biophysical Research Communications·Justin Lowenthal, Sharon Gerecht
Aug 1, 2015·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Yasuhide NakayamaNoriko Okumura
May 8, 2016·The Annals of Thoracic Surgery·Tadahisa SugiuraToshiharu Shinoka
Jun 11, 2016·Colloids and Surfaces. B, Biointerfaces·Chikako SatoMasaru Tanaka
May 10, 2017·Tissue Engineering. Part a·Takuma FukunishiNarutoshi Hibino
Oct 26, 2016·Cardiovascular Engineering and Technology·Inge A E W van LoosdregtCarlijn V C Bouten
Oct 13, 2018·Tissue Engineering. Part B, Reviews·Shigeo IchihashiPetra Mela
Mar 22, 2019·Tissue Engineering. Part B, Reviews·Juan M ColazoWesley P Thayer
Oct 28, 2019·Journal of Biomedical Materials Research. Part a·Haoyong YuanZhongshi Wu
Dec 3, 2016·Biofabrication·Camila A WilkensJuan Pablo Acevedo
Aug 30, 2018·Stem Cells International·Kevin DzoboKeolebogile Shirley Caroline M Motaung
Aug 4, 2016·Journal of Biomaterials Science. Polymer Edition·Zhong-Kui LiSi-Ming Yan
Apr 3, 2020·Nature Communications·Randall J SmithStelios T Andreadis
May 4, 2018·Frontiers in Bioengineering and Biotechnology·Michele Carrabba, Paolo Madeddu
Nov 24, 2020·The International Journal of Artificial Organs·Jin ChengYongquan Gu
Sep 19, 2020·The Annals of Thoracic Surgery·Yuichi MatsuzakiToshiharu Shinoka
May 14, 2021·APL Bioengineering·Qiao ZhangGeorge A Truskey
Sep 21, 2021·Journal of Biomedical Materials Research. Part a·Eri KoyanagiYasumoto Nakazawa

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.