Vessel network formation in response to intermittent hypoxia is frequency dependent

Journal of Bioscience and Bioengineering
Seema M Ehsan, Steven C George

Abstract

A combined experimental and mathematical model of intermittent hypoxia (IH) conditioned engineered tissue was used to characterize the effects of IH on the formation of in vitro vascular networks. Results showed that the frequency of hypoxic oscillations has pronounced influence on the vascular response of endothelial cells and fibroblasts.

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Citations

Aug 30, 2018·Lab on a Chip·Stephanie J Hachey, Christopher C W Hughes
Dec 21, 2018·PloS One·Sandra F LamSteven C George
Mar 11, 2020·Frontiers in Endocrinology·Jiri Pavlacky, Jan Polak
Nov 7, 2019·Nature Biomedical Engineering·Sean V MurphyAnthony Atala

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