Vestibular Disorders in Children With Congenital Cytomegalovirus Infection

Pediatrics
Sophie BernardNatacha Teissier

Abstract

Congenital cytomegalovirus (CMV) infection is the leading infectious cause of neurologic disabilities and sensorineural hearing loss in children. Sensorineural hearing loss prevalence in CMV suggests a viral tropism for the inner ear. Vestibular disorders induced by CMV infection are underestimated. This is the largest and most thorough study to assess the incidence of vestibular disorders and their correlation with hearing thresholds in children with CMV. This retrospective study assessed a cohort of 52 children with congenital CMV infection and sensorineural impairment who received a complete hearing and vestibular assessment. Vestibular evaluation included clinical examination, caloric bithermal test, earth vertical axis rotation, off-vertical axis rotation, and vestibular evoked myogenic potential. The prevalence, progression, and clinical impact of vestibular disorders were studied and correlated with hearing thresholds and the severity of congenital CMV infection. Forty-eight children (92.3%) had hearing loss and vestibular disorders. Of those, vestibular disorders were complete and bilateral in 33.3%, partial and bilateral in 43.7%, and partial and unilateral in 22.9%. Serial testing in 14 children showed stable vestibul...Continue Reading

References

Jun 2, 1977·The New England Journal of Medicine·S StagnoC A Alford
Nov 1, 1968·The Laryngoscope·E N Myers, S Stool
Dec 1, 1969·The Annals of Otology, Rhinology, and Laryngology·G L Davis
Jun 17, 1998·The Journal of Pediatrics·S R Wiener-Vacher, K Mazda
Apr 6, 1999·Archives of Otolaryngology--head & Neck Surgery·S R Wiener-VacherY Manach
Mar 7, 2003·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Gerhard AnderssonHans Christian Larsen
Aug 11, 2004·International Journal of Pediatric Otorhinolaryngology·Rose Marie RineMargaret Shaffer
Apr 26, 2005·Clinical Medicine : Journal of the Royal College of Physicians of London·G M Halmagyi
May 25, 2005·Neurology·Miriam S Welgampola, James G Colebatch
Jun 22, 2005·BMC Public Health·Michael J Cannon, Katherine Finn Davis
Sep 30, 2005·The New England Journal of Medicine·Giovanni NigroUNKNOWN Congenital Cytomegalovirus Collaborating Group
Nov 1, 2005·Brain Research. Cognitive Brain Research·Patrick PéruchMichel Lacour
Sep 2, 2006·International Journal of Pediatric Otorhinolaryngology·Jennifer Braswell, Rose Marie Rine
Jun 21, 2007·Reviews in Medical Virology·Aileen Kenneson, Michael J Cannon
May 20, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·G BenoistY Ville
Sep 30, 2008·International Journal of Audiology·Sylvette R Wiener-Vacher
Jan 13, 2009·Clinical Microbiology Reviews·Maxim C-J CheeranMark R Schleiss
Aug 14, 2009·Journal of Perinatal Medicine·Oriol CollUNKNOWN WAPM Perinatal Infections Working Group
Jun 22, 2010·Reviews in Medical Virology·Michael J CannonTerri B Hyde
Oct 29, 2011·Ear and Hearing·Kathleen M McNerney, Robert F Burkard
Oct 29, 2011·Acta Neuropathologica·Natacha TeissierHoma Adle-Biassette
May 8, 2013·NeuroRehabilitation·Rose Marie Rine, Sylvette Wiener-Vacher
Oct 29, 2014·Pediatrics·Julie GoderisIngeborg Dhooge
Mar 31, 2015·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Guangwei Zhou, Jacob R Brodsky

❮ Previous
Next ❯

Citations

Dec 29, 2015·Current Opinion in Pediatrics·Scott H James, David W Kimberlin
Dec 3, 2015·Research in Developmental Disabilities·Alexandra De KegelHilde Van Waelvelde
Apr 14, 2016·European Annals of Otorhinolaryngology, Head and Neck Diseases·N TeissierT Van Den Abbeele
Aug 18, 2016·Journal of Neurovirology·Huanan LiaoHiroyuki Nakamura
Jul 25, 2017·Audiology & Neuro-otology·Antoine PaulNatalie Loundon
Sep 18, 2018·The Pediatric Infectious Disease Journal·Antonietta GiannattasioFrancesco Raimondi
Nov 26, 2018·Archives of Disease in Childhood·Jenny RetzlerChristine E Jones
May 29, 2019·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Cleo DhondtIngeborg Dhooge
Aug 23, 2019·Chinese Medical Journal·Xin-Yan Zhang, Feng Fang
Jan 1, 2019·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Valentine Faure-BardonMarianne Leruez-Ville
Apr 19, 2017·Italian Journal of Pediatrics·Concetta Marsico, David W Kimberlin
Sep 6, 2019·JCI Insight·Cathy Yea Won SungWilliam Britt
Aug 14, 2019·American Journal of Otolaryngology·Vladimir TsuprunSebahattin Cureoglu
Jan 27, 2021·European Annals of Otorhinolaryngology, Head and Neck Diseases·C CourtoisN Loundon
Feb 4, 2021·Journal of Neurosciences in Rural Practice·Vykuntaraju K GowdaDhananjaya K Vamyanmane
May 9, 2021·Antiviral Research·Shannon A Ross, David Kimberlin
Jun 15, 2021·Frontiers in Neurology·Hajime KoyamaTatsuya Yamasoba
Jul 27, 2021·Otolaryngologic Clinics of North America·Elizabeth A KellyJessie N Patterson
Jan 13, 2021·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Anisha SinghKristal M Riska

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Lymphoproliferative Syndrome

Autoimmune lymphoproliferative syndrome (ALPS) is a rare genetic disorder of abnormal lymphocyte survival caused by defective Fas mediated apoptosis. Discover the latest research on ALPS here.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.

© 2021 Meta ULC. All rights reserved