PMID: 6983810Nov 1, 1982Paper

Vestibulo-oculomotor disturbances in humans exposed to styrene

Acta Oto-laryngologica
L OdkvistS R Liedgren

Abstract

Several reports indicate that disturbances of the vestibulo-oculomotor ability are a manifestation of the toxic action on the central nervous system exerted by some industrial solvents. The aim of the present investigation was to examine the vestibulo-oculomotor system during exposure to styrene, which is extensively used in the production of plastics. Healthy volunteers were exposed to styrene for one hour. Rotatory and optokinetic nystagmus, visual suppression as well as speed, latency and accuracy of saccades were tested before, during, and one hour after the exposure. The pulmonary uptake and the blood level of the solvent were continuously analysed by gas chromatography. The styrene blood concentration was equivalent to that which may well be reached after serveral hours of hard work in an industrial environment with a concentration of styrene within permitted limits. No spontaneous nystagmus appeared. The rotatory and optokinetic nystagmus was not influenced by styrene. However, the speed of the saccade was significantly enhanced. The visual suppression was disturbed, shown by an increased gain after styrene exposure. The experiments thus indicate that styrene given to healthy test persons induced disturbances, thus consi...Continue Reading

References

Feb 1, 1978·Environmental Research·R LilisI J Selikoff
Nov 1, 1977·Acta Oto-laryngologica·G AschanR Tham
May 1, 1979·Acta Pharmacologica Et Toxicologica·R ThamA Bertler
Jan 1, 1979·Advances in Oto-rhino-laryngology·L M OdkvistG Aschan
Jan 27, 1978·International Archives of Occupational and Environmental Health·B LarsbyA Rubin
Dec 1, 1975·Scandinavian Journal of Work, Environment & Health·I Astrand
Sep 1, 1976·Scandinavian Journal of Work, Environment & Health·A M Seppäläinen, H Härkönen
Jul 1, 1967·Archives of Environmental Health·B KylinA Lindborg
May 1, 1968·Archives of Environmental Health·R D StewartA W Schaffer
Jan 1, 1982·Acta Oto-laryngologica·R ThamC Liedgren

❮ Previous
Next ❯

Citations

Aug 21, 2007·Noise & Health·Lyn Hodgkinson, Deepak Prasher
Jan 28, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Carolin Simone FischerMichael Strupp
Sep 21, 2011·International Journal of Audiology·Ewa Zamyslowska-Szmytke, Mariola Sliwinska-Kowalska
Jan 1, 1994·Critical Reviews in Toxicology·C S Rebert, T A Hall
Jan 1, 1987·Scandinavian Audiology·L M OdkvistL M Bergholtz
Dec 1, 1993·Perceptual and Motor Skills·G Groth-Marnat
Apr 8, 1998·Journal of Occupational and Environmental Medicine·C H PierceY So
Feb 7, 2018·International Journal of Occupational Safety and Ergonomics : JOSE·Concetto GiorgianniGiovanna Spatari
Mar 1, 1986·Acta Oto-laryngologica·B LarsbyI Bunnfors
Jan 1, 1984·Acta Pharmacologica Et Toxicologica·R ThamL M Odkvist
Jan 1, 1984·Acta Ophthalmologica. Supplement·J Ignatius

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
M A QuéréF Lavenant
Journal of Occupational and Environmental Medicine
Andrea BaccarelliMustafa Dosemeci
ORL; Journal for Oto-rhino-laryngology and Its Related Specialties
D HydénR Tham
© 2021 Meta ULC. All rights reserved