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Veto T cells enhance engraftment allogeneic hematopoietic stem cells

Zhongguo shi yan xue ye xue za zhi

Jul 7, 2011

Feng LiShu-Quan Ji

PMID: 21729580

Abstract

Veto activity was defined as the capacity of specifically downregulating cytotoxic T-precursor cell (CTL-p) directed against antigens of the veto cells themselves but not against third-party antigens. Many studies have shown that the most potent veto cells are CD8(+) cytotoxic T lymphoc...read more

Mentioned in this Paper

T-Lymphocyte
TC2 Cells
Graft Acceptance
Cytotoxic T-Lymphocytes
Antigens
Hemopoietic Stem Cell Transplant
Regulatory T-Lymphocytes
Transplantation Aspects
Hematopoietic Stem Cells
Natural Immunosuppression
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Veto T cells enhance engraftment allogeneic hematopoietic stem cells

Zhongguo shi yan xue ye xue za zhi

Jul 7, 2011

Feng LiShu-Quan Ji

PMID: 21729580

DOI:

Abstract

Veto activity was defined as the capacity of specifically downregulating cytotoxic T-precursor cell (CTL-p) directed against antigens of the veto cells themselves but not against third-party antigens. Many studies have shown that the most potent veto cells are CD8(+) cytotoxic T lymphoc...read more

Mentioned in this Paper

T-Lymphocyte
TC2 Cells
Graft Acceptance
Cytotoxic T-Lymphocytes
Antigens
Hemopoietic Stem Cell Transplant
Regulatory T-Lymphocytes
Transplantation Aspects
Hematopoietic Stem Cells
Natural Immunosuppression

Similar Papers Found In These Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Immune Tolerance

Immune tolerance happens when the immune system is not responsive to a substance or organism and does not elicit an immune response. This is a normal physiological response for some antigens, especially when detecting self from non-self. This has been a potential area of therapy for some disorders. Here is the latest research on immune tolerance.

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