Vibrational algorithms for quantitative crystallographic analyses of hydroxyapatite-based biomaterials: II, application to decayed human teeth

Analytical and Bioanalytical Chemistry
Tetsuya AdachiNarisato Kanamura

Abstract

A systematic investigation, based on highly spectrally resolved Raman spectroscopy, was undertaken to research the efficacy of vibrational assessments in locating chemical and crystallographic fingerprints for the characterization of dental caries and the early detection of non-cavitated carious lesions. Raman results published by other authors have indicated possible approaches for this method. However, they conspicuously lacked physical insight at the molecular scale and, thus, the rigor necessary to prove the efficacy of this spectroscopy method. After solving basic physical challenges in a companion paper, we apply them here in the form of newly developed Raman algorithms for practical dental research. Relevant differences in mineral crystallite (average) orientation and texture distribution were revealed for diseased enamel at different stages compared with healthy mineralized enamel. Clear spectroscopy features could be directly translated in terms of a rigorous and quantitative classification of crystallography and chemical characteristics of diseased enamel structures. The Raman procedure enabled us to trace back otherwise invisible characteristics in early caries, in the translucent zone (i.e., the advancing front of t...Continue Reading

References

Jan 1, 1973·Scandinavian Journal of Dental Research·I J Möller, S Poulsen
Jan 1, 1982·Caries Research·J M ten Cate, P P Duijsters
Nov 1, 1995·Advances in Dental Research·D T Zero
Nov 1, 1995·Advances in Dental Research·W M Edgar, S M Higham
Mar 23, 1999·Community Dentistry and Oral Epidemiology·J D Featherstone
Jan 2, 2001·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C RobinsonJ Kirkham
May 2, 2001·European Journal of Oral Sciences·A LussiP Francescut
Jan 11, 2002·Community Dentistry and Oral Epidemiology·J D BaderA J Bonito
Dec 12, 2002·Journal of Public Health Dentistry·James D BaderArthur J Bonito
Jan 31, 2003·The Journal of the American Dental Association·Carol Anne Murdoch-Kinch, Mary Ellen McLean
Aug 3, 2004·Journal of Dental Research·J D B Featherstone
May 25, 2006·Physical Chemistry Chemical Physics : PCCP·Marta CornoPiero Ugliengo
Apr 15, 2009·Proceedings of the National Academy of Sciences of the United States of America·Herzl ChaiBrian R Lawn
Jan 9, 2006·Optics Express·Alex C-T KoBlaine Cleghorn
Oct 27, 2009·Brazilian Oral Research·Jaime Aparecido Cury, Livia Maria Andaló Tenuta
Mar 1, 2010·Journal of Research of the National Institute of Standards and Technology·B D Schmuck, C M Carey
Sep 11, 2012·Journal of Dentistry·Maisoon Al-JawadChristian J Hendriksz
Feb 13, 2015·Analytical and Bioanalytical Chemistry·Giuseppe PezzottiNarisato Kanamura

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Citations

Sep 3, 2016·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Giuseppe PezzottiNarisato Kanamura
Jul 27, 2017·Lasers in Medical Science·Shino NakamuraMatsuo Yamamoto

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