Vibrational spectra of DNA in the confined interglobular volume of photonic crystal

Journal of Biological Physics
V V BoikoGalyna Dovbeshko

Abstract

The impact of confinement of DNA molecules in a limited volume of the cavity of photonic crystals (PC) on the vibrational properties of the DNA molecule and its conformation is studied. According to our preliminary study, the aqueous shell is removed when the DNA molecules are infiltrated into the PC cavities. Raman scattering (RS) DNA marker lines showed a dramatic conformational change of DNA in the PC cavities and the appearance of new unknown conformational states. We observed the enhancement of vibrational modes of DNA in the PC in comparison with free DNA of about tenfold and the absence of vibrational modes in DNA bases in a region of 1450-1700 cm-1. The observed features in the RS spectra of DNA are explained by the impact of confined interglobular volume and strong localization of the electromagnetic field. Namely, FDTD simulations in linear regime demonstrate the localization of light in cavities of PC with an approximately ninefold enhancement of the electric field within the photonic stop-band, which is the main reason for RS amplification.

References

Jan 1, 1990·The International Journal of Biochemistry·M GhomiE Taillandier
Jul 1, 1984·Biopolymers·M H Zehfus, W C Johnson
Feb 1, 1984·Biopolymers·B PrescottG J Thomas
Mar 1, 1997·Biophysical Journal·M D WangS M Block
Jan 1, 1997·Biopolymers·V A Bloomfield
Jun 6, 2003·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·C Storm, P C Nelson
Apr 2, 2004·Nature Materials·Marin Soljacić, J D Joannopoulos
Dec 13, 2005·Genome Research·Michael L Metzker
Apr 1, 2008·Journal of the American Chemical Society·Aoune BarhoumiNaomi J Halas
Jul 26, 2008·Nature Nanotechnology·Nikhil GaneshBrian T Cunningham
Sep 29, 2011·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Jeong Sun SohnByung Wook Jo
Aug 24, 2013·The Analyst·Weili ChenBrian T Cunningham
Sep 30, 2014·The Analyst·Weili ChenBrian T Cunningham
Apr 9, 2015·Nanoscale Research Letters·Vitalii BoikoVladimir Gorelik
Oct 31, 2015·Physical Chemistry Chemical Physics : PCCP·O DeparisB-L Su

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