Vibrationally coherent photochemistry in the femtosecond primary event of vision

Science
Q WangC V Shank

Abstract

Femtosecond pump-probe experiments reveal the impulsive production of photoproduct in the primary event in vision. The retinal chromophore of rhodopsin was excited with a 35-femtosecond pulse at 500 nanometers, and transient changes in absorption were measured with 10-femtosecond probe pulses. At probe wavelengths within the photo-product absorption band, oscillatory features with a period of 550 femtoseconds (60 wavenumbers) were observed whose phase and amplitude demonstrate that they are the result of nonstationary vibrational motion in the ground state of the photoproduct. The observation of coherent vibrational motion of the photoproduct supports the idea that the primary step in vision is a vibrationally coherent process and that the high quantum yield of the cis-->trans isomerization in rhodopsin is a consequence of the extreme speed of the excited-state torsional motion.

Citations

Oct 18, 2006·Journal of Computer-aided Molecular Design·Marius WankoMarcus Elstner
Dec 24, 2011·Visual Neuroscience·Sadaharu MiyazonoClint L Makino
Nov 14, 2001·Biochemistry·J E KimR A Mathies
Jan 6, 2012·Biochemistry·Min-Hsuan ChenBarry E Knox
Dec 8, 2011·Journal of the American Chemical Society·Goran ZgrablićFulvio Parmigiani
Nov 10, 2011·Journal of the American Chemical Society·Amir WandSanford Ruhman
Jan 11, 2012·Journal of the American Chemical Society·Yang YangKarsten Heyne
Nov 24, 2011·Journal of the American Chemical Society·Peter W KimDelmar S Larsen
May 25, 2013·Journal of the American Chemical Society·Shengshuang ZhuScott E Feller
Jul 4, 2008·Journal of the American Chemical Society·Minoru KuboPaul M Champion
Dec 31, 2008·Journal of the American Chemical Society·Izumi IwakuraTakayoshi Kobayashi
Dec 10, 2009·Journal of the American Chemical Society·Petra H M Bovee-GeurtsWillem J Degrip
Mar 23, 2006·The Journal of Physical Chemistry. a·Judy E Kim, Richard A Mathies
Mar 14, 2012·The Journal of Physical Chemistry. a·Adam D DunkelbergerF Fleming Crim
Feb 17, 2010·The Journal of Physical Chemistry. B·Venugopal KarunakaranPaul M Champion
Mar 20, 2010·Physical Chemistry Chemical Physics : PCCP·Julien BriandStefan Haacke
Oct 29, 2011·Physical Chemistry Chemical Physics : PCCP·Jan Philip KraackMarcus Motzkus
Dec 13, 2012·Faraday Discussions·Thomas S KuhlmanTodd J Martínez
May 30, 2008·Proceedings of the National Academy of Sciences of the United States of America·Janne SavolainenJennifer L Herek
Oct 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Peter G Wolynes
Nov 15, 2012·Proceedings of the National Academy of Sciences of the United States of America·Paul Brumer, Moshe Shapiro
May 28, 1996·Proceedings of the National Academy of Sciences of the United States of America·K Lao, A N Glazer
Sep 7, 2001·Proceedings of the National Academy of Sciences of the United States of America·D K Jacobs, D R Lindberg
Nov 22, 2007·Photochemistry and Photobiology·Lan-Ying Yang, Robert S H Liu
Jan 24, 2009·Photochemistry and Photobiology·Konstantin NikolicPatrick Degenaar
Nov 15, 2005·Science·Paul M Champion
Sep 8, 2012·Science·Samer GozemMassimo Olivucci
Mar 25, 2010·Biochemistry. Biokhimii︠a︡·O A SmitienkoM A Ostrovsky
Oct 16, 2008·Doklady. Biochemistry and Biophysics·O A SmitienkoM A Ostrovsky
Jan 1, 1997·Annual Review of Biophysics and Biomolecular Structure·W D HoffJ L Spudich
Feb 13, 2007·Annual Review of Physical Chemistry·Benjamin G Levine, Todd J Martínez
Sep 26, 2007·Annual Review of Physical Chemistry·Villy Sundström
Dec 10, 2002·Annual Review of Physiology·Sławomir FilipekKrzysztof Palczewski
Apr 10, 2009·The Journal of Chemical Physics·Sandy YangTodd J Martínez
Sep 1, 2006·The Journal of Chemical Physics·Patrick NuernbergerFabrizio Santoro
Dec 11, 2007·The Journal of Chemical Physics·Ryosuke NakamuraYasuo Kanematsu
Apr 5, 2011·The Journal of Chemical Physics·Maja KobusGerhard Stock
Oct 22, 2005·The Journal of Chemical Physics·Mayumi AbeWolfgang Domcke

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