Video-assisted thoracoscopic surgery versus open surgery for Stage I thymic epithelial tumours: a propensity score-matched study

European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery
Zhitao GuMembers of the Chinese Alliance for Research in Thymomas

Abstract

Video-assisted thoracoscopic surgery (VATS) has been increasingly used in the management of thymic epithelial tumours. However, its oncological efficacy remains to be proved. The purpose of this study is to compare the oncological outcomes following thoracoscopic versus open surgery in the case-matched groups of patients with early-stage thymic tumours from the Chinese Alliance for Research in Thymomas (ChART) retrospective database. Between 1994 and 2012, a total of 1087 patients who underwent surgery for UICC (Union for International Cancer Control) pathological Stage I tumours from the ChART retrospective database were recruited for this study. A propensity score-matched analysis was used to compare the long-term outcomes in patients who received VATS or open surgery. VATS resection was performed in 271 patients (24.9%) and open surgery in 816 patients (75.1%). Before propensity score matching, the VATS group had a smaller tumour size (P = 0.002), lower grade histology (P = 0.034), lower T stage (P < 0.001) and less adjuvant therapy (P < 0.001). Propensity score matching by gender, myasthenia gravis, tumour size, histological classification, pathological T stage, extent of thymectomy, adjuvant radiotherapy and adjuvant chemo...Continue Reading

References

Nov 28, 2000·The Annals of Thoracic Surgery·J C RückertJ M Müller
Mar 24, 2005·The Thoracic and Cardiovascular Surgeon·A TokerG Kalayci
Nov 25, 2005·The Annals of Thoracic Surgery·Wentao FangYong Jiang
Jan 18, 2006·Journal of Pediatric Surgery·Amy J WagnerHanmin Lee
May 15, 2010·American Journal of Surgery·Samuel J YoussefEric Vallières
Jan 25, 2011·The Journal of Thoracic and Cardiovascular Surgery·Arjun PennathurJames D Luketich
Jul 4, 2012·The Annals of Thoracic Surgery·Julissa JuradoJoshua R Sonett
Mar 13, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Imthiaz ManolyEdwin Woo
Apr 16, 2014·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Zhi-Tao GuWentao Fang
Nov 15, 2014·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Frank C DetterbeckUNKNOWN Participating Institutions of the Thymic Domain
Jan 15, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Adam J FriedantWalter J Scott
Apr 27, 2016·Journal of Thoracic Disease·Wentao FangUNKNOWN Members of the Chinese Alliance for Research in Thymomas
Apr 27, 2016·Journal of Thoracic Disease·Hao WangUNKNOWN Members of the Chinese Alliance for Research in Thymomas
Aug 28, 2016·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Bryan M BurtWalter Scott
Apr 28, 2017·Annals of Cardiothoracic Surgery·Olugbenga T OkusanyaJames D Luketich
Jun 18, 2017·The Annals of Thoracic Surgery·Hiroyuki AgatsumaHiroshi Niwa

❮ Previous
Next ❯

Citations

Aug 1, 2020·Frontiers in Neurology·Maria Elena Farrugia, John A Goodfellow
Jun 5, 2021·The Annals of Thoracic Surgery·Timothy J HolleranGregory D Trachiotis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2022 Meta ULC. All rights reserved