Viewing a forelimb induces widespread cortical activations

NeuroImage
Vassilis RaosH E Savaki

Abstract

Given that prerequisite of activating the mirror neuron system is the preshaping of the hand and its interaction with the object during observation of a reaching-to-grasp-an-object action, the effects of viewing the object, the reaching forelimb and the static hand may obscure the effects of observing the grasping action per se. To disentangle these effects, we employed the (14)C-deoxyglucose quantitative autoradiographic method to map the functional activity in the entire cortex of monkeys (Macaca mulatta) which observed the experimenter performing non-goal-directed (purposeless) forelimb movements towards an object that was previously presented but no longer visible. Thus, our monkeys were exposed to the view of an object, a moving arm and a static hand with extended wrist and fingers. The distribution of metabolic activity was analyzed in 20μm thick brain sections, and two dimensional maps were reconstructed in the occipital operculum, the temporal, the lateral and medial parietal, the lateral and medial frontal, the lateral prefrontal and orbitofrontal cortices, including the cortex within the lunate, superior temporal, lateral, parietoccipital, intraparietal, central, arcuate and principal sulci. Increased metabolic activi...Continue Reading

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Citations

Sep 8, 2016·Cerebral Cortex·Vassilis Raos, Helen E Savaki
Mar 29, 2014·Journal of Cognitive Neuroscience·Alan D A MattiassiCosimo Urgesi
Dec 12, 2018·Cerebral Cortex·Vassilis Papadourakis, Vassilis Raos
Apr 4, 2019·Cognitive, Affective & Behavioral Neuroscience·Wuyi WangChiang-Shan R Li
Jan 22, 2020·Experimental Brain Research·Rafael V BretasAtsushi Iriki
Apr 1, 2021·ELife·Justine C CléryStefan Everling
Jul 15, 2021·Cerebral Cortex·Helen E SavakiPanagiotis G Simos
Aug 20, 2021·Cerebral Cortex Communications·Vassilis Raos, Helen E Savaki

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