Vigorous exercise as a triggering mechanism for late stent thrombosis: A description of three cases

Platelets
Bastiaan ZwartArnoud W J Van 't Hof

Abstract

Although (very) late coronary stent thrombosis is a rare complication after percutaneous coronary interventions (PCI), its consequences are devastating with a high morbidity and mortality. Previous studies have identified several clinical, procedural and angiographic characteristics that are associated with stent thrombosis but little is known about the underlying mechanisms that induce, provoke or trigger the of stent thrombosis. In the present paper, we describe three patients who suffered from a stent thrombosis immediately after vigorous exercise. Patient 1 suffered a stent thrombosis (ST) after performing an in-hospital bicycle ergometer test, 6 weeks after an acute coronary syndrome. Patient 2 suffered from ST immediately following his first excessive endurance cycling tour, more than 2 years after myocardial infarction. Patient 3 suffered ST while performing vigorous exercise on a bicycle ergometer in a fitness centre. These findings implicate that ST might be triggered by vigorous exercise, especially in untrained patients. Further research after triggering mechanisms of ST is urgently warranted.

References

Dec 1, 1975·Angiology·A BlackG Gensini
Jun 1, 1989·The Journal of Clinical Investigation·J B GordonA P Selwyn
Oct 1, 1993·Circulation·A S KestinA D Michelson
Nov 24, 1999·JAMA : the Journal of the American Medical Association·S GiriD D Waters
Sep 19, 2000·Medicine and Science in Sports and Exercise·B E AinsworthA S Leon
Nov 9, 2000·The New England Journal of Medicine·C M AlbertJ E Manson
Oct 3, 2002·Circulation·Raymond J GibbonsUNKNOWN American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1997 Ex
Oct 29, 2002·International Journal of Sports Medicine·T HilbergH H Gabriel
Dec 1, 2004·Arteriosclerosis, Thrombosis, and Vascular Biology·Jong-Shyan WangYu-Wen Chen
May 5, 2005·JAMA : the Journal of the American Medical Association·Ioannis IakovouAntonio Colombo
Mar 15, 2006·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Darren E R WarburtonShannon S D Bredin
Jul 4, 2006·Journal of the American College of Cardiology·Michael JonerRenu Virmani
Aug 26, 2006·Journal of Biomedical Science·Jong-Shyan Wang
Dec 7, 2006·JAMA : the Journal of the American Medical Association·Eric L EisensteinRobert M Califf
May 2, 2007·Circulation·Donald E CutlipUNKNOWN Academic Research Consortium
Mar 8, 2008·Journal of the American College of Cardiology·José M de la Torre-HernándezUNKNOWN ESTROFA Study Group
Apr 18, 2009·Journal of the American College of Cardiology·Jochem W van WerkumJurriën M ten Berg

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Citations

Sep 16, 2010·Current Treatment Options in Cardiovascular Medicine·Bastiaan ZwartJurriën M Ten Berg
Jun 22, 2010·Journal of Cardiothoracic and Vascular Anesthesia·Prakash A Patel, John G T Augoustides
Feb 26, 2011·JACC. Cardiovascular Interventions·Karim D MahmoudDavid R Holmes
Jul 23, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Jun 9, 2016·The Journal of Nutrition, Health & Aging·T NickelM Halle

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