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Vildagliptin, a DPP-4 Inhibitor, Attenuates Endothelial Dysfunction and Atherogenesis in Nondiabetic Apolipoprotein E-Deficient Mice

International Heart Journal

Nov 15, 2019

Kunduziayi AiniMasataka Sata

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Abstract

Dipeptidyl peptidase-4 (DPP-4) inhibitors are novel antidiabetic agents with possible vascular protection effects. Endothelial dysfunction is an initiation step in atherogenesis. The purpose of this study was to investigate whether vildagliptin (Vilda) attenuates the development of endo...read more

Mentioned in this Paper

Analogs & derivatives
Aortic Arch Structure
Apolipoprotein E
Atherosclerosis
Blood Glucose
Blood Vessel
Cell Adhesion Molecules
Endothelium
Endothelium, Vascular
Hyperlipoproteinemia Type III
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Vildagliptin, a DPP-4 Inhibitor, Attenuates Endothelial Dysfunction and Atherogenesis in Nondiabetic Apolipoprotein E-Deficient Mice

International Heart Journal

Nov 15, 2019

Kunduziayi AiniMasataka Sata

PMID: 31735774

DOI: 10.1536/ihj.19-117

Abstract

Dipeptidyl peptidase-4 (DPP-4) inhibitors are novel antidiabetic agents with possible vascular protection effects. Endothelial dysfunction is an initiation step in atherogenesis. The purpose of this study was to investigate whether vildagliptin (Vilda) attenuates the development of endo...read more

Mentioned in this Paper

Analogs & derivatives
Aortic Arch Structure
Apolipoprotein E
Atherosclerosis
Blood Glucose

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