Abstract
Acute respiratory infections (ARIs) are the leading cause of infectious disease-related morbidity, hospitalization, and morbidity among children worldwide. This study aimed to assess the viral and bacterial causes of ARI morbidity and mortality in children under 5 years in Senegal. Nasopharyngeal samples were collected from children under 5 years who had ARI. Viruses and bacteria were identified using multiplex real-time reverse transcription-polymerase chain reaction and conventional biochemical techniques, respectively. Adenovirus was the most prevalent virus (50%; n = 81), followed by influenza virus (45.68%, n = 74), rhinovirus (40.12%; n = 65), enterovirus (25.31%; n = 41), and respiratory syncytial virus (16.05%; n = 26), whereasStreptococcus pneumoniae(17%; n = 29),Moraxella catarrhalis(15.43%; n = 25), andHaemophilus influenzae(8.02%; n = 13) were the most commonly isolated bacteria. Virus pathogens seem more likely to be more prevalent in our settings and were often associated with bacteria andS. pneumoniae(6%; 16) coinfection.
References
Jun 24, 1998·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J FanL L Savatski
Mar 15, 2002·The Lancet Infectious Diseases·Brian G WilliamsChristopher Dye
Oct 21, 2009·Antimicrobial Agents and Chemotherapy·Patrick D MauldinJohn A Bosso
May 3, 2011·PloS One·Patrícia G M BezerraPaul S McNamara
Apr 12, 2012·Virology Journal·Theophilus B KwofieMichael Owusu
Nov 12, 2013·The Journal of Infection·Chidi N ObasiJames Gern
Apr 11, 2014·The Pediatric Infectious Disease Journal·Tal MaromTasnee Chonmaitree
Apr 15, 2014·Journal of Infection in Developing Countries·Derya Çağlayan SerinUNKNOWN Pneumonia Study Group
Jun 8, 2014·The Journal of Infectious Diseases·Nicole WolterAnne von Gottberg
Jun 17, 2014·PloS One·Sandra A AsnerDominik Mertz
Nov 2, 2014·PloS One·Solange OuédraogoMarie Gueudin
Apr 19, 2015·BMC Infectious Diseases·Paul SimusikaMwaka Monze
Nov 17, 2015·BMC Infectious Diseases·Adamou LagareStefano Tempia
Mar 26, 2016·Influenza and Other Respiratory Viruses·Sebastien KenmoeRichard Njouom
Mar 23, 2017·PloS One·Mbayame Ndiaye NiangNdongo Dia
Citations
Mar 24, 2020·BMJ Global Health·Kristoffer Jarlov JensenChristine Stabell Benn
Jul 16, 2020·Influenza and Other Respiratory Viruses·Abu Tholib AmanChuen-Yen Lau
Jan 23, 2019·BMC Infectious Diseases·Stephanie Saiki-MacedoJuana Del Valle-Mendoza
Jan 8, 2020·Microbiology Insights·Rebecca B KnobbeCheikh Sb Boye
Sep 17, 2020·African Journal of Laboratory Medicine·Cheikh FallAmadou A Sall
Jan 20, 2021·Revue des maladies respiratoires·S PilletA Vabret
Oct 29, 2020·Wellcome Open Research·Irene Wangwa AdemaD James Nokes
Feb 28, 2021·Diagnostic Microbiology and Infectious Disease·Justin HardickUNKNOWN Emergency Department National Network Influenza Investigators
Mar 12, 2021·Influenza and Other Respiratory Viruses·Sebastien KenmoeRichard Njouom
Sep 8, 2021·Frontiers in Cellular and Infection Microbiology·Ying LiDi Liu