Viral coinfection in children less than five years old with invasive pneumococcal disease

The Pediatric Infectious Disease Journal
Cristian LaunesC Muñoz-Almagro

Abstract

Seventy-one patients <5 years of age who were hospitalized with invasive pneumococcal disease were studied in the period between August 2008 and December 2009. The purpose was to determine the proportion of episodes that were coinfected with respiratory virus. Viral coinfection was common (44/71; 62%), with rhinovirus and influenza virus being the most frequently detected. Highly invasive serotypes (1, 5, 7F, 14, 19A) were found in 31 of 71 patients, of whom 15 had viral coinfection (15/31; 48%). Viral detection occurred significantly more often in those episodes caused by nonhighly invasive serotypes (29/40; 72%), suggesting that a viral synergism could help those serotypes to make invasiveness more likely.

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Citations

Feb 6, 2013·Current Infectious Disease Reports·Carmen Muñoz-AlmagroRoman Pallares
Jan 5, 2013·The Journal of Infectious Diseases·Emily T MartinJanet A Englund
Aug 1, 2013·The Journal of Infectious Diseases·Daniel M WeinbergerHelle B Konradsen
Dec 20, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Anu GoenkaRachel Kneen
Jan 15, 2014·European Journal of Pediatrics·D S KlobassaW Zenz
Jul 1, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C LaunesC Muñoz-Almagro
Mar 22, 2014·Journal of Clinical Laboratory Analysis·Jeffrey M BenderElizabeth M Marlowe
Apr 2, 2014·Respiratory Medicine·Reetika SuriJonathan Grigg
Feb 20, 2015·Emerging Infectious Diseases·Adoración Navarro-TornéUNKNOWN Invasive Pneumococcal Disease Study Group
Jan 30, 2015·Frontiers in Cellular and Infection Microbiology·Yashuan ChaoAnders P Hakansson
Aug 12, 2014·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J BurgosV Falco
May 6, 2014·Vaccine·Adoración Navarro TornéUNKNOWN ECDC country experts for pneumococcal disease
Apr 20, 2017·Molecular Microbiology·Cyril GuilhenDamien Balestrino

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