PMID: 9658148Jul 11, 1998Paper

Viral determinants of rotavirus pathogenicity in pigs: evidence that the fourth gene of a porcine rotavirus confers diarrhea in the homologous host

Journal of Virology
J C BridgerU Desselberger

Abstract

A porcine rotavirus (prv) monoreassortant, S-F4, which carries RNA segment 4 of the pig-pathogenic variant prv 4F in the genetic background of the pig-apathogenic variant prv 4S (G. I. Tauscher and U. Desselberger, J. Virol. 71:853-857, 1997), was found to be pathogenic in gnotobiotic piglets. This indicates that RNA segment 4 of the pig-pathogenic variant prv 4F is a major determinant of pathogenicity in its homologous host.

References

Jan 1, 1976·The Journal of Infectious Diseases·A Torres-MedinaA Z Kapikian
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Jan 1, 1986·Journal of Virology·P A OffitH F Clark
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Apr 15, 1996·Virology·B Burke, U Desselberger

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Citations

Feb 17, 2005·Journal of Medical Virology·Larry E WestermanRoger I Glass
Aug 26, 2011·Journal of Virology·Marco CaporaleMassimo Palmarini
Oct 7, 2006·Current Opinion in Gastroenterology·R D Shaw
Sep 21, 2001·Journal of Medicinal Chemistry·A FazliM von Itzstein
Aug 3, 2016·Annual Review of Virology·Susana LópezCarlos F Arias

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