Viral FLIPping autophagy for longevity.

Cell Host & Microbe
Chengyu Liang

Abstract

Tumor-causing γ-herpesviruses have evolved elaborate mechanisms to deal with almost every aspect of host cell defense. In this issue of Cell Host & Microbe, Leidal et al. (2012) report an oncogenic synergy between the latent KSHV proteins v-FLIP and v-cyclin during KSHV persistent infection that reshapes autophagy.

References

Jan 15, 2008·Cell·Beth Levine, Guido Kroemer
Mar 7, 2009·Biochimica Et Biophysica Acta·Sanae Shoji-Kawata, Beth Levine
Mar 13, 2009·Genes & Development·Andrew R J YoungMasashi Narita
Oct 20, 2009·Nature Cell Biology·Jong-Soo LeeJae U Jung
Dec 26, 2009·Current Opinion in Cell Biology·Zhifen Yang, Daniel J Klionsky
Apr 7, 2010·The Journal of Clinical Investigation·Don Ganem
Sep 3, 2010·Current Opinion in Cell Biology·Vassilis G Gorgoulis, Thanos D Halazonetis

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