Viral targets for vaccines against COVID-19.

Nature Reviews. Immunology
Lianpan Dai, George F Gao

Abstract

Vaccines are urgently needed to control the coronavirus disease 2019 (COVID-19) pandemic and to help the return to pre-pandemic normalcy. A great many vaccine candidates are being developed, several of which have completed late-stage clinical trials and are reporting positive results. In this Progress article, we discuss which viral elements are used in COVID-19 vaccine candidates, why they might act as good targets for the immune system and the implications for protective immunity.

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Methods Mentioned

BETA
in vitro transcription
bronchoalveolar lavage

Clinical Trials Mentioned

ISRCTN89951424
ISRCTN14722499
NCT04456595
NCT04582344
NCT04617483
NCT04612972
NCT04560881
NCT04470609
NCT04526990
NCT04540419

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