PMID: 1195517Jun 1, 1975Paper

Virologic and serologic studies on an outbreak of echovirus type 11 infection in a hospital maternity unit

Japanese Journal of Medical Science & Biology
A Hasegawa

Abstract

An outbreak of echovirus type 11 (E-11) infection occurred among newborn babies in a hospital maternity unit in the summer of 1971. The results of studies are as follows: 1) Forty-one of 188 infants developed febrile illness with stomatitis during one and a half months from July to September. E-11 was isolated from stool specimens of 14 infants and two throat swabs. Antibody response to the virus was shown in all the 19 cases examined. Some of their mothers were suffering from subclinical infection. 2) The isolates were identified as a variant of E-11 which is not neutralized with antiserum against prototype E-11. Antiserum against the current virus neutralized both current and prototype viruses. 3) Sucrose gradient centrifugation of sera from infants revealed that the neutralizing antibody activity resided more predominantly in 19S than in 7S fractions. These antibodies reacted more specifically with the current strain than with the prototype Gregory strain.

References

Mar 1, 1973·The Journal of Pediatrics·A G Philip, E J Larson
Jun 1, 1973·Japanese Journal of Medical Science & Biology·I Tagaya, Y Moritsugu
Jan 1, 1972·American Journal of Diseases of Children·J R HughesE de Hoyos-Guevara
Jan 1, 1968·The Journal of Pediatrics·S Berkovich, E M Smithwick
Aug 1, 1958·A.M.A. Journal of Diseases of Children·A B SABINR WIGAND
Mar 1, 1959·The Journal of Clinical Investigation·S J ZAK, R A GOOD
Jul 1, 1964·British Journal of Preventive & Social Medicine·J B LANDSMANC A ROSS

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Citations

Aug 1, 1990·Journal of Medical Virology·K MatsumotoY Kimura

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