PMID: 6990482Apr 12, 1980Paper

Virologic diagnosis of rubella. Findings in a rubella epidemic in a military training camp

Schweizerische medizinische Wochenschrift
F BurkhardtH Saner

Abstract

During a minor rubella epidemic in a Swiss army recruit training camp (Spring 1978), recent rubella infection was proved in 20 out of 22 investigated cases. In 18 cases virus replication could be shown by means of indirect immunofluorescence (IIF). Due to its higher sensitivity and easier performance in comparison with conventional echo interference, we believe IIF should be the method of choice for rubella virus isolation. In 2 out of 22 cases, the possibility of a secondary infection was discussed. A chceklist is given showing the necessary steps for virological investigations we think should be carried out to define immunity status, confirm or rule out a rubella infection, particular weight being attached to the embryopathy question. This article is therefore intended to provide the clinician interested in virological problems with a total to enable him to take the necessary measures for detection of rubella infection and interpretation of laboratory findings.

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