Virtual colonoscopy with magnetic resonance imaging: in vitro evaluation of a new concept

Gastroenterology
A W SchoenenbergerJ F Debatin

Abstract

Screening for colonic polyps is desirable. A new concept based on cross-sectional and endoscopic analysis of a magnetic resonance (MR) data set is presented. Ex vivo autopsy colonic specimens, containing artificially placed polyps, were obtained and filled with a gadolinium-containing solution. Forty-four thin-section MR images were obtained in a 1.5-T MR scanner in 28 seconds. A three-dimensional endoscopic fly-through of these images was rendered. Fly-throughs and two-dimensional cross-sectional images were analyzed by two observers for the presence of polyps. The average sensitivity and specificity for the detection of polyps based on three-dimensional endoscopic MR colon imaging were 87% and 96%, respectively. Analysis of cross-sectional images showed an overall sensitivity and specificity of merely 57% and 84%, respectively. The difference in the interpretation of three-dimensional MR colonoscopy and two-dimensional cross-sections was statistically significant (P < 0.001). With three-dimensional MR colonoscopy, overall sensitivity for detection of polyps measuring < or =5 mm in length and diameter was 70%; for larger polyps, it increased to 95% (P < 0.01). The feasibility of an MR-based endoluminal assessment of the colon ...Continue Reading

Citations

Dec 8, 2009·La Presse médicale·Ulriikka ChaputStanislas Chaussade
Oct 23, 2001·Seminars in Ultrasound, CT, and MR·T C Lauenstein, J F Debatin
Jan 3, 2001·AJR. American Journal of Roentgenology·M M MorrinR R Edelman
Aug 14, 2001·Journal of Clinical Gastroenterology·R Sander, U Frankenberger
Aug 13, 1999·The American Journal of Gastroenterology·A SonnenbergP Bauerfeind
Aug 5, 2000·Radiology·C D Johnson, A H Dachman
May 19, 2019·Environmental Science and Pollution Research International·Qiang LiAugustus Boadi Owusu
May 29, 2010·Environmental Science and Pollution Research International·Akhila RayaLu-Kwang Ju
Dec 23, 2003·The American Journal of Gastroenterology·Wai K LeungJoseph J Y Sung
Aug 5, 2000·Radiology·W LuboldtJ F Debatin
May 12, 2006·World Journal of Gastroenterology : WJG·Rahime HaykirErtugrul Kayacetin
Jun 27, 2000·Gastroenterology·S Mallery, J Van Dam

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