Virucidal activity of the new disinfectant monopercitric acid

Letters in Applied Microbiology
P Wutzler, Andreas Sauerbrei

Abstract

The virucidal efficacy of monopercitric acid (MPCA) was evaluated against the enveloped vaccinia virus as well as the nonenveloped adenovirus type 2 and poliovirus type 1. The results were compared with that obtained with peracetic acid (PAA). In the virucidal suspension test without and with protein burden, all viruses were inactivated by 0.5% MPCA within 0.5 min or by 0.1% MPCA within 5 min as measured by a >10(4)-fold reduction in virus titres. For MPCA, there was a better virucidal efficacy than for PAA which inactivated all viruses included in the test within 15-30 min at a concentration of 0.2%. The high virucidal activity, short exposure times, and nontoxic by-products seem to make MPCA suitable as disinfectant for medical use and should warrant further investigation.

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Citations

Nov 29, 2008·Archives of Virology·Andreas Sauerbrei, P Wutzler
Jun 2, 2009·The Journal of Hospital Infection·A SauerbreiP Wutzler
Jun 12, 2010·Letters in Applied Microbiology·A Sauerbrei, P Wutzler
Jan 24, 2007·The Journal of Hospital Infection·A SauerbreiP Wutzler
Oct 3, 2006·The Journal of Hospital Infection·A SauerbreiP Wutzler
Nov 25, 2014·Food and Environmental Virology·Allison VimontJulie Jean
Feb 26, 2015·Brazilian Oral Research·Solange Alves da Silva CostaSilvana Soléo Ferreira dos Santos
Jun 30, 2005·Current Opinion in Infectious Diseases·Markus Dettenkofer, Colin Block
Sep 4, 2020·ChemPlusChem·Lili LiangGrzegorz Lisak
Oct 20, 2018·Frontiers in Microbiology·Riikka LinnakoskiVarpu Marjomäki

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