Virucidal properties of metal oxide nanoparticles and their halogen adducts

Nanoscale
Johanna HäggströmGeorge Marchin

Abstract

Selected metal oxide nanoparticles are capable of strongly adsorbing large amounts of halogens (Cl(2), Br, I(2)) and mixed halogens. These solid adducts are relatively stable thermally, and they can be stored for long periods. However, in the open environment, they are potent biocides. Herein are described studies with a number of bacteriophage MS2, phiX174, and PRD-1 (virus examples). PRD-1 is generally more resistant to chemical disinfection, but in this paper it is shown to be very susceptible to selected interhalogen and iodine adducts of CeO(2), Al(2)O(3), and TiO(2) nanoparticles. Overall, the halogen adducts of TiO(2) and Al(2)O(3) were most effective. The mechanism of disinfection by these nanoparticles is not completely clear, but could include abrasive properties, as well as oxidative powers. A hypothesis that nanoparticles damage virons or stick to them and prevent binding to the host cell is a consideration that needs to be explored. Herein are reported comparative biocidal activities of a series of adducts and electron microscope images of before and after treatment.

References

Nov 1, 1982·Applied and Environmental Microbiology·M E Alvarez, R T O'Brien
Oct 16, 2003·Journal of the American Chemical Society·Peter K StoimenovKenneth J Klabunde
Jan 20, 2004·Advances in Renal Replacement Therapy·Pon Jola Coney
Dec 13, 2005·Structure·Stephen Fuller
Mar 17, 2006·International Journal of Food Microbiology·Yashpal S Malik, Sagar M Goyal
Feb 13, 2007·Water Environment Research : a Research Publication of the Water Environment Federation·Ernest R BlatchleyJohn T Lisle
Mar 28, 2007·Current Opinion in Structural Biology·Juha T Huiskonen, Sarah J Butcher
Apr 10, 2007·Proceedings of the National Academy of Sciences of the United States of America·Juha T HuiskonenSarah J Butcher

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bacteriophage: Phage Therapy

Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.