PMID: 9423887Jan 10, 1998Paper

Virulence of a Salmonella typhimurium OmpD mutant

Infection and Immunity
P N MeyerRoy Curtiss

Abstract

An ompD mutation caused by a Tn10 insertion was transduced into Salmonella typhimurium SL1344 and UK-1. The adherence and invasion capabilities of the resultant ompD mutants were examined by tissue culture analysis. The virulence of the S. typhimurium ompD mutants was ascertained by a 50% lethal dose (LD50) study and by determining colonization ability with BALB/c mice. We found no statistically significant difference in adherence and invasion capacities between the S. typhimurium wild type strains and their corresponding ompD mutants. Furthermore, the LD50 and colonization studies revealed that there is no statistically significant difference in virulence between the S. typhimurium wild type strains and their corresponding ompD mutants. These results differ from those reported previously (C. J. Dorman, S. Chatfield, C. F. Higgins, C. Hayward, and G. Dougan, Infect. Immun. 57:2136-2140, 1989).

References

Aug 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·J E Galán, R Curtiss
Mar 1, 1985·Microbiological Reviews·H Nikaido, M Vaara
Dec 1, 1987·Infection and Immunity·P A Gulig, R Curtiss
May 1, 1986·Reviews of Infectious Diseases·R Edelman, M M Levine
Jan 1, 1993·Journal of Bacteriology·S K CollinsonW W Kay
Apr 1, 1996·Infection and Immunity·M R Wilmes-RiesenbergR Curtis
Oct 1, 1957·Journal of Bacteriology·S E LURIA, J W BURROUS
Jul 1, 1991·Journal of Food Protection·Robert V Tauxe

❮ Previous
Next ❯

Citations

Jan 13, 2005·Canadian Journal of Microbiology·Bochiwe Hara-Kaonga, Thomas G Pistole
Oct 7, 2006·Current Opinion in Gastroenterology·A Ljungh
Jun 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·Cristina Gil-CruzAdam F Cunningham
Jun 24, 2010·The Journal of Microbiology·Hyun-Ju Kim, Hyon E Choy
Dec 14, 2006·Molecular Microbiology·Alexandra SittkaJörg Vogel
Oct 28, 2020·Journal of Bacteriology·Aryashree ArunimaMrutyunjay Suar
Oct 20, 2017·Omics : a Journal of Integrative Biology·Aryashree ArunimaMrutyunjay Suar
Sep 1, 2010·EcoSal Plus·Satoshi Yamashita, Susan K Buchanan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.