PMID: 6408816Apr 15, 1983Paper

Virus hepatitis C as an immunologically and clinically defined form of non-A, non-B hepatitis. A contribution to the diagnosis, clinical aspects, paraclinical aspects, course, prognosis and prevention of this disease

Zeitschrift für die gesamte innere Medizin und ihre Grenzgebiete
H Porst

Abstract

After the detection of a non-A/non-B-associated antigen/antibody system--identity with the system of Shirachi and co-workers--we analysed clinical and paraclinical data of 106 women after application of contaminated anti-D-immunoglobulin. Of 106 infected female patients 84 fell ill manifest, 22 cases showed typical prodromi of hepatitis. The incubation time could exactly be calculated with 55 days (+/- s = 11). Apart from the parenteral the non-parenteral possibility of transmission could be proved. Remarkable are 50% of chronic cases three years after infection. As favourable markers of prognosis juvenile age, appearance of prodromi and clinical symptoms as well as signs of cholestasis are to be mentioned.

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