Virus PCR assay panels: an alternative to the mouse antibody production test

Lab Animal
Walter A BlankLisa A White

Abstract

Antibody production tests have traditionally been used to test biological materials for viral contamination. Now molecular biology techniques have emerged as an alternative. The authors compare MAP testing with PCR-based detection methods, focusing on differences in animal use, laboratory requirements, sample size, and limits of detection.

References

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Citations

May 29, 2008·ILAR Journal·David G BesselsenLela K Riley
Feb 6, 2014·Laboratory Animals·UNKNOWN FELASA working group on revision of guidelines for health monitoring of rodents and rabbitsM Raspa
Jun 4, 2020·Viruses·Luís Guilherme de OliveiraIgor R H Gatto
Dec 5, 2009·Current Protocols in Stem Cell Biology·Richard Josephson, Jonathan Auerbach

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Methods Mentioned

BETA
PCR
enzyme-linked immunosorbent
electrophoresis
serum collection
ELISA
nucleic acid extraction
nucleic

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