Visceral leishmaniasis without splenomegaly. A pediatric case report

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
C LeblancL De Pontual

Abstract

Pediatric visceral leishmaniasis is caused by Leishmania infantum, a dog parasite transmitted to humans by the bite of the female phlebotomine sand fly. The well-known clinical triad is fever, pallor, and splenomegaly. A secondary macrophage activation syndrome (MAS) can complicate this infection, which is lethal when not treated. When MAS is observed without any explanation, a visceral leishmaniasis is highly recommended. We report a case of visceral leishmaniasis in a 21-month-old child complicated by a macrophage activation syndrome without splenomegaly. No immunodeficiency was diagnosed that could explain this unusual clinical condition. To our knowledge, this is the first case of visceral leishmaniasis without splenomegaly reported to date.

References

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Oct 20, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·P MartyE Rosenthal
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Jan 27, 2015·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·L HigelA Belot

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Citations

Mar 22, 2019·Tropical Doctor·Mirella Alves CunhaHenio Godeiro Lacerda

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