Visceral obesity and incident cancer and cardiovascular disease: An integrative review of the epidemiological evidence.

Obesity Reviews : an Official Journal of the International Association for the Study of Obesity
Erika Aparecida SilveiraCesar de Oliveira

Abstract

Evidence shows a strong relationship between obesity, cancer and cardiovascular disease (CVD) risk. However, there is not enough evidence of the role of visceral obesity on both CVD and cancer. Visceral obesity may be more pro-oncogenic than total body fat. Therefore, it is important to know whether abdominal obesity can lead to both CVD and cancer. The present integrative review aimed at evaluating epidemiological evidence on the potential connection of visceral obesity in the occurrence of cancer and CVD. The following databases were searched: SCOPUS, PubMed, Science Direct, Lilacs, SciELO, Google Scholar, Web of Science, Scopus and ProQuest. The presence of visceral obesity can increase the risk of some specific cancer types, but there is controversial evidence about CVD risk based on sex-specific and ageing analyses. There is enough evidence that visceral obesity increases the risk of colorectal, pancreatic and gastro-oesophageal cancer. However, for some types of cancer such as breast, endometrial and renal, visceral obesity is a risk only in post-menopausal women. Regarding prostate cancer, the evidence is controversial. Despite the risk of visceral obesity being consistently associated with CVD in adults, this associatio...Continue Reading

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Citations

Nov 5, 2020·International Journal of Molecular Sciences·Lucia La Sala, Antonio E Pontiroli
Dec 3, 2020·International Journal of Molecular Sciences·Erika Aparecida SilveiraCesar de Oliveira
May 1, 2021·Cancers·Tero SievänenElina Sillanpää
May 14, 2021·BMC Gastroenterology·Erika Aparecida SilveiraCesar de Oliveira

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Methods Mentioned

BETA
biopsy

Software Mentioned

Scopus
ProQuest
Google Scholar

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