Visible chemiluminescence from rat brain homogenates undergoing autoxidation. I. Effect of additives and products accumulation

Journal of Free Radicals in Biology & Medicine
E A LissiL A Videla

Abstract

Rat brain homogenate autoxidation was assessed from thiobarbituric acid reactant accumulation (TBAR), light emission, and oxygen uptake. The effect of several additives upon TBAR accumulation and light intensity suggests that these parameters can be employed as a reliable measure of the lipoperoxidation extent. From the different time profiles of TBAR accumulation and light emission, it is concluded that instantaneous light emission is not a measure of the lipoperoxidation rate but it is related to the accumulation of products. The time dependence of the light emitted after addition to an incubated sample of an excess of free radical scavengers indicates that at least two intermediates of widely different lifetimes are contributing to the observed light emission.

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Citations

Nov 3, 1992·Biochemical Pharmacology·A I CederbaumH Speisky
Jan 1, 1992·Free Radical Biology & Medicine·E A LissiL A Videla
Dec 1, 1995·Free Radical Biology & Medicine·I AzorinJ Renau-Piqueras
Apr 7, 2005·Neuroscience Research·Daniela DelwingAngela T S Wyse
Jan 4, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·A WhiteR Martínez
Jun 20, 2007·Photochemistry and Photobiology·Carolina AliagaTito Scaiano
Jan 1, 1987·Free Radical Biology & Medicine·T IwaokaT Takahashi
Jul 3, 2007·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Carolina D PederzolliCarlos S Dutra-Filho
Oct 18, 2005·Bioresource Technology·M A NascimentoM G Almeida
Oct 20, 2000·Luminescence : the Journal of Biological and Chemical Luminescence·A Aspée, E A Lissi
Jan 2, 2007·Neurochemistry International·Angela M SgaravattiCarlos Severo Dutra-Filho
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Jul 8, 2008·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Angela M SgaravattiCarlos Severo Dutra-Filho
Jul 30, 2020·Chemistry & Biodiversity·Cecilia DobreckyPablo Evelson
Jan 1, 1989·Free Radical Research Communications·E A LissiL A Videla
Feb 16, 2015·Molecular and Cellular Biochemistry·Andrea Pereira RosaCarlos Severo Dutra-Filho
Feb 4, 2014·Metabolic Brain Disease·Tarsila Barros MoraesCarlos Severo Dutra-Filho
Jun 11, 1993·Neuroscience Letters·M SubramanianT P Devasagayam
Jan 1, 1994·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·H Speisky, B K Cassels

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