Visible-Light-Mediated Photocatalytic Difunctionalization of Olefins by Radical Acylarylation and Tandem Acylation/Semipinacol Rearrangement

Chemistry : a European Journal
Carl-Johan WallentinCarl-Johan Wallentin

Abstract

A novel method for the mild photoredox-mediated tandem radical acylarylation and tandem acylation/semipinacol rearrangement has been developed. The synthesis of highly functionalized ketones bearing all-carbon α- or β-quaternary centers has been achieved using easily available symmetric aromatic carboxylic anhydrides as the acyl radical source. The method allows for a straightforward introduction of the keto functionality and concomitant construction of molecular complexity in a single operation.

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Citations

Apr 13, 2017·Journal of the American Chemical Society·Mattia SilviVarinder K Aggarwal
Apr 13, 2017·Chemistry : a European Journal·Fredrik PetterssonCarl-Johan Wallentin
Jul 4, 2019·Chemical Society Reviews·Alexey A FestaErik V Van der Eycken
Oct 3, 2018·Chemical Record : an Official Publication of the Chemical Society of Japan ... [et Al.]·Shaista Sultan, Bhahwal Ali Shah
May 26, 2018·Chemistry : a European Journal·Shaista SultanBhahwal Ali Shah
Jul 1, 2020·IScience·Xiao-Qiang HuYang Gao
May 27, 2020·Organic Letters·Promita BiswasJoyram Guin
Jan 7, 2021·Organic Letters·Yuliang LiuShunsuke Chiba
Jul 17, 2018·Chemical Reviews·Chang-Sheng WangJean-François Soulé
Sep 30, 2021·Angewandte Chemie·Yuan-Yuan ChengLi-Zhu Wu

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