Vision impairment after traumatic brain injury: present knowledge and future directions

Reviews in the Neurosciences
Mahasweta DasSubhra Mohapatra

Abstract

Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the USA as well as in the world. As a result of TBI, the visual system is also affected often causing complete or partial visual loss, which in turn affects the quality of life. It may also lead to ocular motor dysfunction, defective accommodation, and impaired visual perception. As a part of the therapeutic strategy, early rehabilitative optometric intervention is important. Orthoptic therapy, medication, stem cell therapy, motor and attention trainings are the available treatment options. Gene therapy is one of the most promising emerging strategies. Use of state-of-the-art nanomedicine approaches to deliver drug(s) and/or gene(s) might enhance the therapeutic efficacy of the present and future modalities. More research is needed in these fields to improve the outcome of this debilitating condition. This review focuses on different visual pathologies caused by TBI, advances in pre-clinical and clinical research, and available treatment options.

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Citations

Mar 14, 2020·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Na ChenLongqian Liu
Jun 4, 2019·Journal of Neuroinflammation·Mahasweta DasSubhra Mohapatra
Oct 9, 2020·Investigative Ophthalmology & Visual Science·Lucy P EvansAlexander G Bassuk
Jun 5, 2021·Scientific Reports·Nickolas A BoehmeLaura M Dutca
Jul 29, 2021·Military Medical Research·Syeda F HussainRenata S M Gomes

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