Visual activation in functional magnetic resonance imaging at very high field (4 Tesla)

Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
A MikiJ C Haselgrove

Abstract

Functional magnetic resonance imaging (fMRI) at very high field strengths provides functional brain mapping with the enhanced signal to noise ratio and the larger blood oxygenation level-dependent (BOLD) effect. We report activated areas in the standard space detected by fMRI at 4 Tesla (T) during simple visual stimulation. Twelve healthy young subjects were scanned using a 4 T scanner during binocular flashing visual stimulation. Functional images were realigned to the first scan and then spatially normalized. Individual and group data analyses were performed to identify areas of visual activation. Activation of the bilateral primary visual cortex (V1/V2) was observed along the entire calcarine fissure in all subjects. The activated area extended to the extrastriate cortex in all subjects. Activation of the bilateral lateral geniculate nucleus (LGN) was detected in all subjects. The group data showed activation of the bilateral primary visual cortex and the bilateral lateral geniculate nucleus. Robust activation of the vision-related areas was successfully obtained in all subjects using a 4 T magnetic resonance scanner. These results suggest that fMRI at very high field strengths may be effective in showing visual system physi...Continue Reading

References

Jul 1, 1992·Proceedings of the National Academy of Sciences of the United States of America·S OgawaK Ugurbil
Nov 1, 1990·Archives of Neurology·J C HortonW F Hoyt
Mar 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R S MenonK Uğurbil
Feb 1, 1993·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R TurnerR S Balaban
Jan 1, 1993·Journal of Neurophysiology·S G KimK Ugurbil
Aug 1, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·J S GatiB K Rutt
Nov 14, 1997·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·C BüchelK Friston
Jun 1, 1997·NMR in Biomedicine·K R ThulbornJ T Voyvodic
Jan 23, 1998·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·W ChenK Ugurbil
Jul 29, 1998·Brain : a Journal of Neurology·C BüchelK J Friston
Jul 1, 1999·NeuroImage·K J FristonK J Worsley
Jul 2, 1999·Topics in Magnetic Resonance Imaging : TMRI·K R Thulborn
Aug 31, 1999·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·K UğurbilA Georgopoulos
Sep 10, 1999·Experimental Brain Research·S SunaertG A Orban

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Citations

Jan 4, 2005·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Atsushi MikiJohn C Haselgrove
Jul 3, 2009·Neurosurgical Focus·John S Pezaris, Emad N Eskandar
Oct 7, 2004·Human Brain Mapping·Katharina NebelMatthias Keidel
Dec 6, 2001·Current Opinion in Ophthalmology·A MikiJ C Haselgrove

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