PMID: 9181334Jan 1, 1996Paper

Visual acuity and scar size in eyes with age-related subfoveal choroidal neovascular lesions, 30 months after radiation therapy

Documenta Ophthalmologica. Advances in Ophthalmology
G J BergnikW A van Daal

Abstract

In a study to determine the effectiveness of ionizing radiation on the deterioration of visual acuity (VA) due to choroidal neovascularisation (CNV) the affected eyes of 10 patients were treated with a total dose of 24 Gy (6 Gy fractions). A special lens-sparing technique was used to avoid cataract development. During 30 months of follow-up the visual acuity (VA) and scar size (SS) of the treated eyes and fellow eyes of all 10 patients were evaluated. After 30 months of follow-up 5 eyes showed a stable VA and fluorescein angiogram (FA) appearance. Concerning 4 out of 5 eyes with progressive disease, the 4 eyes treated with radiation therapy had better VA and smaller SS as compared with the untreated fellow eyes with exudative AMD. The results suggest that 24 Gy either stabilizes or delays the deleterious effects of CNV on the visual acuity. Until now no late side effects have been observed.

References

Oct 1, 1994·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·G J BerginkR W van der Maazen
Jun 1, 1995·The British Journal of Ophthalmology·P M HartU Chakravarthy
Jun 15, 1993·American Journal of Ophthalmology·K B FreundJ A Sorenson
Oct 1, 1993·The British Journal of Ophthalmology·A C Bird
Mar 30, 1995·International Journal of Radiation Oncology, Biology, Physics·K B GordonR H Sagerman
May 1, 1993·The British Journal of Ophthalmology·U ChakravarthyD B Archer
Jan 1, 1995·Documenta Ophthalmologica. Advances in Ophthalmology·G J BerginkR M van der Maazen
Jun 1, 1996·Ophthalmology·P T FingerJ L Bosworth

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Citations

May 20, 1999·American Journal of Ophthalmology·D H CharS Kroll
Jun 30, 2000·Clinical Eye and Vision Care·T J Stokkermans
Jul 22, 1999·The British Journal of Ophthalmology·M Mauget-FaÿsseF Koenig

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