Visual computed tomographic scoring of emphysema and its correlation with its diagnostic electrocardiographic sign: the frontal P vector

Journal of Electrocardiology
Lovely ChhabraDavid H Spodick


Verticalization of the frontal P vector in patients older than 45 years is virtually diagnostic of pulmonary emphysema (sensitivity, 96%; specificity, 87%). We investigated the correlation of P vector and the computed tomographic visual score of emphysema (VSE) in patients with established diagnosis of chronic obstructive pulmonary disease/emphysema. High-resolution computed tomographic scans of 26 patients with emphysema (age, >45 years) were reviewed to assess the type and extent of emphysema using the subjective visual scoring. Electrocardiograms were independently reviewed to determine the frontal P vector. The P vector and VSE were compared for statistical correlation. Both P vector and VSE were also directly compared with the forced expiratory volume at 1 second. The VSE and the orientation of the P vector (ÂP) had an overall significant positive correlation (r = +0.68; P = .0001) in all patients, but the correlation was very strong in patients with predominant lower-lobe emphysema (r = +0.88; P = .0004). Forced expiratory volume at 1 second and ÂP had almost a linear inverse correlation in predominant lower-lobe emphysema (r = -0.92; P < .0001). Orientation of the P vector positively correlates with visually scored emphy...Continue Reading


Jul 1, 1985·Journal of Electrocardiology·K IkedaS Yasui
Feb 1, 1974·Journal of Electrocardiology·S S ZambranoDavid H Spodick
May 15, 1998·Respiration; International Review of Thoracic Diseases·M HaraguchiK Shirato
Mar 20, 1999·Clinical Cardiology·R Baljepally, David H Spodick
Mar 1, 1960·The American Journal of Cardiology·D LITTMANN
Jul 10, 2007·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Laxman PrajapatDavid H Spodick
Jan 20, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Shin MatsuokaHiroto Hatabu
Apr 14, 2010·The Canadian Journal of Cardiology·Rajakrishnan Vijayakrishnan, David H Spodick
Feb 11, 2011·The American Journal of Cardiology·Anish J ThomasDavid H Spodick


Feb 5, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Rishi BajajDavid H Spodick
May 22, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Lovely ChhabraDavid H Spodick
Dec 3, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Swapnil S LanjewarDavid H Spodick
Jul 9, 2013·Journal of Electrocardiology·Lovely ChhabraDavid H Spodick
May 24, 2017·Open Heart·Marte Strømsnes LarssenKnut Gjesdal

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Electrocardiographic Recorders
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