Visual evoked potentials in the vicinity of the optic tract during stereotactic pallidotomy

Electroencephalography and Clinical Neurophysiology
S TobimatsuM Kato

Abstract

We recorded visual evoked responses in eight patients with Parkinson's disease, using a depth electrode either at or below the stereotactic target in the ventral part of the globus pallidus internus (GPi), which is located immediately dorsal to the optic tract. Simultaneously, scalp visual evoked potentials (VEPs) were also recorded from a mid-occipital electrode with a mid-frontal reference electrode. A black-and-white checkerboard pattern was phase reversed at 1 Hz; check size was 50 min of arc . Pallidal VEPs to full field stimulation showed an initial positive deflection, with a latency of about 50 ms (P50), followed by a negatively with a mean latency of 80 ms (N80). The mean onset latency of P50 was about 30 ms. P50 and N80 were limited to the ventralmost of the GPi and the ansa lenticularis. Left half field stimulation evoked responses in the right ansa lenticularis region while right half field stimulation did not, and vice versa. These potentials thus seemed to originate posterior to the optic chiasm. The scalp VEPs showed typical triphasic wave forms consisting of N75, P100 and N145. The location of the recording electrode in the ansa lenticularis region did not modify the scalp VEP. These results suggest that P50 and...Continue Reading

References

May 1, 1992·Electroencephalography and Clinical Neurophysiology·C E SchroederS J Givre
Jan 1, 1992·Stereotactic and Functional Neurosurgery·L V LaitinenM I Hariz
Mar 1, 1988·Electroencephalography and Clinical Neurophysiology·A DucatiE D Motti
May 13, 1999·Nature Neuroscience·W D HutchisonJ O Dostrovsky

❮ Previous
Next ❯

Citations

Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·K ArakawaM Kato
Feb 19, 2000·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·A TzelepiI Bodis-Wollner
Apr 1, 2006·Neuromodulation : Journal of the International Neuromodulation Society·Xuguang LiuTipu Z Aziz
Jul 28, 2009·Journal of Neurosurgery·Takahiro OtaNobuhito Saito
Oct 17, 2012·The Journal of Physiology·Takao HashimotoTetsuya Goto
Mar 7, 2006·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Shozo Tobimatsu, Gastone G Celesia
Feb 13, 2004·Brain : a Journal of Neurology·Andrea A KühnPeter Brown
Aug 26, 2017·Journal of Neurosurgery·Tal ShaharZvi Ram
Jun 23, 2015·Anesthesia and Analgesia·Irene RozetMonica S Vavilala

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.