Abstract
The purpose of this study was to compare standard automated perimetry (SAP) and frequency-doubling technology (FDT) perimetry for detecting macular damage in glaucoma. A total of 112 glaucomatous eyes with localized retinal nerve fiber layer defects on red-free photographs and corresponding macular ganglion cell/inner plexiform layer (mGC/IPL) thinning on the deviation map of macular optical coherence tomography, and 35 healthy eyes were enrolled in the study. All participants underwent SAP 24-2, SAP 10-2, FDT 24-2, and FDT 10-2 visual field (VF) tests. Significantly depressed points, with confidence limits of 5% and 1%, were checked for in the pattern deviation plots of the VF tests. Detection rate of the macular damage, sensitivity, and specificity were compared among various VF tests. Patients were divided into eyes with mGC/IPL thinning within the normative database, depressed <5% or <1%. Comparison of VF parameters between various VF tests were performed according to the degree of mGC/IPL thinning. All of the macular damage in glaucoma were detected using FDT 10-2 and 83.3% to 90.0% were detected using FDT 24-2 when the mGC/IPL thickness was <5%. Even when mGC/IPL thickness was within normal range, the detection rate of ma...Continue Reading
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