PMID: 8949687Sep 1, 1996Paper

Visual function and perinatal focal cerebral infarction

Archives of Disease in Childhood. Fetal and Neonatal Edition
E MercuriL Dubowitz

Abstract

To evaluate the visual function of infants with perinatal cerebral infarction in whom the site and size of the lesion has been determined using magnetic resonance imaging (MRI). Twelve infants with cerebral infarction on MRI were studied with a battery of tests specifically designed to evaluate visual function in infancy. This included tests: for visual attention (fixation shifts); of cerebral asymmetry (optokinetic nystagmus, visual fields); for assessment of acuity (forced choice preferential looking); and neurophysiological measures of vision (phase reversal and orientation reversal visual evoked potential). A considerable incidence of abnormalities on at least one of the tests for visual function used was observed. The presence or severity of visual abnormalities could not always be predicted by the site and extent of the lesion seen on imaging. Early focal lesions affecting the visual pathway can, to some extent, be compensated for by the immature developing brain. These data suggest that all the infants presenting with focal lesions need to be investigated with a detailed assessment of various aspects of vision.

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Citations

Aug 19, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Giovanni BaranelloEugenio Mercuri
Dec 5, 2006·Archives of Disease in Childhood. Fetal and Neonatal Edition·Daniela RicciEugenio Mercuri
Apr 27, 1999·The British Journal of Ophthalmology·P M PennefatherW Tin
May 18, 1999·Archives of Disease in Childhood. Fetal and Neonatal Edition·E MercuriJ Atkinson
Jan 30, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·J AtkinsonJ Rennie
Nov 7, 2003·Archives of Disease in Childhood. Fetal and Neonatal Edition·E MercuriJ Atkinson
Jul 9, 2010·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Francesca GalliniEugenio Mercuri
Jan 9, 2010·The Journal of Pediatrics·Daniela RicciEugenio Mercuri
Nov 22, 2007·Early Human Development·Eugenio MercuriDaniela Ricci
Jul 20, 2007·Developmental Medicine and Child Neurology·D RicciE Mercuri
Jun 22, 2010·Developmental Medicine and Child Neurology·Andrea GuzzettaGiovanni Cioni
May 10, 2012·Developmental Medicine and Child Neurology·Janette Atkinson, Oliver Braddick
Mar 2, 2011·Vision Research·Oliver Braddick, Janette Atkinson
Feb 28, 2006·Early Human Development·Daniela RicciEugenio Mercuri
Oct 9, 2007·Progress in Brain Research·Janette Atkinson, Oliver Braddick
Jan 1, 1997·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·E MercuriL M Dubowitz
Jun 18, 1998·Developmental Medicine and Child Neurology·J van Hof-van DuinA Boldrini

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