Visual function in patients with choroidal neovascularization resulting from age-related macular degeneration: the importance of looking beyond visual acuity

Optometry and Vision Science : Official Publication of the American Academy of Optometry
Donald C Fletcher, Ronald A Schuchard

Abstract

A detailed understanding of overall quality of vision may help primary care physicians, optometrists, and general ophthalmologists to improve the care of patients with choroidal neovascularization (CNV) resulting from age-related macular degeneration (AMD). Published literature was reviewed using Medline searches and the authors' knowledge of the field. Both visual acuity and contrast sensitivity are strongly associated with the ability to perform vision-related activities of daily living. CNV resulting from AMD often leads to scotoma, which is also strongly associated with the ability to perform everyday activities such as reading and driving. Contrast sensitivity and visual field extent may be better predictors of many abilities than visual acuity. Laser photocoagulation, verteporfin therapy, and pegaptanib sodium have been proven to reduce the risk of visual acuity loss in patients with CNV resulting from AMD. Laser photocoagulation frequently causes scotoma, but data on its effects on other aspects of overall quality of vision are scarce. Verteporfin therapy has been shown to also reduce the risk of contrast sensitivity loss and has been associated with stabilization or reduction of scotoma size. Treatment effects beyond vi...Continue Reading

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Jan 22, 2013·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Ann E ElsnerMatthew S Muller
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May 11, 2018·BioMed Research International·Agnieszka KalinowskaRobert Rejdak

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