Visual Guidance of Smooth Pursuit Eye Movements

Annual Review of Vision Science
Stephen G Lisberger

Abstract

Smooth pursuit eye movements provide a model system for studying how visual inputs are transformed into commands for accurate movement. The neural circuit for pursuit eye movements is largely known and has strong parallels to the circuits for many other movements. Here, we outline progress in defining the conceptual operations that are performed by the pursuit circuit and in aligning those functions with neural circuit mechanisms. We discuss how the visual motion that drives pursuit is represented in the visual cortex, and how the visuomotor circuits decode that representation to estimate target direction and speed and to create motor commands. We outline a modulatory influence called gain control that evaluates the reliability and value of visual inputs and programs appropriate motor activity. Future research on pursuit in nonhuman primates holds the potential to reveal, at an unprecedented level of detail, how visuomotor circuits create coordinated actions.

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Citations

Dec 19, 2017·Optometry and Vision Science : Official Publication of the American Academy of Optometry·Esther G GonzálezMartin J Steinbach
May 19, 2017·Journal of Neurophysiology·Philipp KreyenmeierMiriam Spering
Jun 16, 2018·Journal of Vision·Nicolas DeravetPhilippe Lefèvre
Mar 2, 2018·Journal of Neurology·Berno U H OverbeekRaymond T C M Koopmans
Oct 13, 2018·PLoS Computational Biology·Joseph A LombardoLeslie C Osborne
Oct 18, 2019·Journal of Vision·Xiuyun Wu, Miriam Spering
Jul 10, 2019·Journal of Vision·Alexander GoettkerKarl R Gegenfurtner
Nov 28, 2019·Neuropsychopharmacology Reports·Kentaro MoritaRyota Hashimoto
Jul 6, 2018·Biomedizinische Technik. Biomedical Engineering·Beibei ZhangZhao Lv
Oct 13, 2017·PloS One·Jéssica Bruna Santana SilvaNatanael Antonio Dos Santos
Feb 11, 2020·Frontiers in Systems Neuroscience·Seolmin KimJoonyeol Lee
May 7, 2020·Journal of Neurophysiology·Deborah A BaranyTarkeshwar Singh
Jul 10, 2019·Neural Plasticity·Ewa Niechwiej-SzwedoAgnes M F Wong
Dec 29, 2020·Journal of Neurophysiology·Jonathan D CoutinhoGunnar Blohm
Mar 19, 2021·Journal of Vision·Hiu Mei ChowMiriam Spering
Mar 4, 2021·Journal of Neurophysiology·Benedict Wild, Stefan Treue
May 30, 2021·Proceedings of the National Academy of Sciences of the United States of America·Yorie NakahiraJohn C Doyle
Aug 25, 2021·Current Biology : CB·Alexander GoettkerKarl R Gegenfurtner
Sep 15, 2021·PLoS Computational Biology·Giulio MatteucciDavide Zoccolan

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