Visualization of acupuncture meridians in the hypodermis of rat using Trypan blue

Journal of Acupuncture and Meridian Studies
Byung-Cheon Lee, Kwang-Sup Soh

Abstract

Bonghan Kim claimed that the primo-vessel (Bonghan duct) and the primo-node (Bonghan corpuscle) are anatomical structures corresponding to acupuncture meridians and acupoints, respectively, but this claim has not been confirmed. Recently we found that Trypan blue preferentially stained primo-vessels and primo-nodes on the surfaces of internal organs, not staining other structures like blood or lymph vessels or nerves. In this work, we applied Trypan blue to visualize the putative acupuncture meridian along skin skeletal muscles in the hypodermal layer of a rat. The Trypan blue stained-structures are morphologically similar to the meridian primo-vessels, as claimed by Bonghan Kim. Further study is needed to investigate the network of these Trypan blue-stained structures in order to establish them as acupuncture meridians.

References

Jun 2, 2004·The Anatomical Record. Part B, the New Anatomist·Byung-Cheon LeeKwang-Sup Soh
May 18, 2005·The Anatomical Record. Part B, the New Anatomist·Hak-Soo ShinKwang-Sup Soh
Sep 24, 2005·The Anatomical Record. Part B, the New Anatomist·Byung-Cheon LeeKwang-Sup Soh
Oct 5, 2006·Microscopy Research and Technique·Byung-Cheon LeeByung-Soo Chang
Mar 8, 2007·Evidence-based Complementary and Alternative Medicine : ECAM·Hyeon-Min JohngKwang-Sup Soh
Dec 1, 2008·Journal of Acupuncture and Meridian Studies·Soo Jae LeeKwang-Sup Soh
Mar 1, 2009·Journal of Acupuncture and Meridian Studies·Byung-Cheon LeeKwang-Sup Soh
Mar 1, 2009·Journal of Acupuncture and Meridian Studies·Byung-Cheon LeeKwang-Sup Soh

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Citations

Aug 13, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Sang Hyun ParkYeon-Hee Ryu
Apr 23, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Eun-Sung ParkDong-Ho Youn
Sep 18, 2015·Evidence-based Complementary and Alternative Medicine : ECAM·Chae Jeong LimPan Dong Ryu
Aug 30, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Chae Jeong LimPan Dong Ryu
Feb 9, 2012·Journal of Acupuncture and Meridian Studies·Jiří PokornýAlberto Foletti
Dec 26, 2012·Journal of Acupuncture and Meridian Studies·Lawrence Leung
Jul 17, 2010·Journal of Acupuncture and Meridian Studies·Byung-Cheon LeeKwang-Sup Soh
Jun 28, 2011·Journal of Acupuncture and Meridian Studies·So Rim KimPan Dong Ryu
Jun 14, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Ding-Jun CaiFan-Rong Liang
Mar 16, 2019·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Nikola TomovNikolay Dimitrov
Jul 3, 2016·Cold Spring Harbor Protocols·Lisa C CrowleyNigel J Waterhouse
May 22, 2020·Journal of Acupuncture and Meridian Studies·Linlin Zhang, Sang Wook Oh
Jan 9, 2016·The Journal of the American Osteopathic Association·Bruno ChiklyJörgen Quaghebeur
Oct 10, 2021·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Shan-Qiang ZhangJi-Cheng Li
Nov 10, 2021·Biomaterials Science·Shuyao RuanNianping Feng

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