Visualization of age-dependent myocardial metabolic impairment in cardiomyopathic model hamster obtained by fluorescent X-ray computed tomography using I-127 BMIPP

Journal of Synchrotron Radiation
Thet-Thet-LwinTakao Akatsuka

Abstract

Fluorescent X-ray computed tomography (FXCT) enables visualization of myocardial fatty acid metabolism by using non-radio-iodinated I-5-(p-iodophenyl)-3-(R,S)-methylpentadecanoice acid (BMIPP). In this experiment, age-dependent myocardial metabolic impairment was successfully imaged and analyzed quantitatively in J2N-k cardiomyopathic hamster using FXCT.

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