Visualization of small glottic laryngeal cancer using methyl-labeled 11C-methionine positron emission tomography

Oral Oncology
J WedmanB F A M van der Laan

Abstract

Despite abundant literature on the use of PET in head and neck cancer, a little is known about the visualization of small laryngeal cancer. Moreover, most literature deals with the radiopharmaceutical (18)F-fludeoxyglucose (FDG), whereas only a few papers address the use of (11)C labeled amino acids. This study was performed to evaluate the feasibility of (11)C-labeled methionine in visualizing small laryngeal cancer. Ten patients with a de novo small laryngeal cancer (7 T1, 3 T2) underwent a MET PET at least 3 weeks after biopsy but prior to further treatment. Static scans were made in 'whole body' mode, covering the head from the external auditory meatus downwards to the whole thorax. The resulting images were judged by experienced specialists in nuclear medicine, who assessed the relative visibility of each tumor on a 3-point scale. Nine tumors were visualized (5 clearly, 4 moderately). One (T1) was not visualized. Small laryngeal cancer can be visualized with (11)C-methionine PET.

References

Nov 14, 1998·Clinical Nuclear Medicine·H J KimV Lowe
Dec 2, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·J NuutinenH Minn
Apr 29, 2000·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M LapelaH Minn
Apr 27, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Dan RibomAnja Smits
Aug 23, 2002·European Journal of Nuclear Medicine and Molecular Imaging·Jurjan R de BoerWillem Vaalburg
Nov 19, 2003·Archives of Otolaryngology--head & Neck Surgery·David L SchwartzJanet Eary
Jan 15, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Kazuo KubotaHiroshi Fukuda
Jul 1, 2001·European Journal of Nuclear Medicine·E KresnikP Lind

❮ Previous
Next ❯

Citations

Dec 28, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jan WedmanBernard F A M van der Laan
Sep 18, 2016·Critical Reviews in Oncology/hematology·Giuditta MannelliOreste Gallo
Oct 14, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Jan WedmanBernard F A M van der Laan
May 4, 2016·Nuclear Medicine Communications·Natale QuartuccioUNKNOWN Young AIMN Working Group
Oct 23, 2019·Seminars in Ultrasound, CT, and MR·Laura B Eisenmenger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Esther G C TroostJohannes H A M Kaanders
Otolaryngologic Clinics of North America
Ari M Blitz, Nafi Aygun
Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
Grażyna NiedzielskaDanuta Toman
Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
Yoon Kyoung SoYoung-Ik Son
© 2021 Meta ULC. All rights reserved