Visualizing new dimensions in Drosophila myoblast fusion.

BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology
Brian E RichardsonMary K Baylies

Abstract

Over several years, genetic studies in the model system, Drosophila melanogastor, have uncovered genes that when mutated, lead to a block in myoblast fusion. Analyses of these gene products have suggested that Arp2/3-mediated regulation of the actin cytoskeleton is crucial to myoblast fusion in the fly. Recent advances in imaging in Drosophila embryos, both in fixed and live preparations, have led to a new appreciation of both the three-dimensional organization of the somatic mesoderm and the cell biology underlying myoblast fusion.

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Jul 21, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jing MiaoJie Ding
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Aug 3, 2010·Experimental Cell Research·Vanessa TixierKrzysztof Jagla

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