Visually induced initiation of Drosophila innate courtship-like following pursuit is mediated by central excitatory state

Nature Communications
Soh Kohatsu, Daisuke Yamamoto

Abstract

The courtship ritual of male Drosophila represents an innate behaviour that is initiated by female-derived sensory stimuli. Here we report that moving light spots can induce courtship-like following pursuit in tethered wild-type male flies provided the fly is primed by optogenetic stimulation of specific dsx-expressing neuronal clusters in the lateral protocerebrum (LPR). Namely, stimulation of the pC1 neuronal cluster initiates unilateral wing extension and vibration of both sides, whereas stimulation of the pC2l cluster initiates only contralateral wing displays. In addition, stimulation of pC2l but not pC1 neurons induced abdominal bending and proboscis extension. Ca(2+) imaging of the pC1 cluster revealed periodic Ca(2+) rises, each corresponding to a turn of the male fly during courtship. In contrast, group-reared fru mutant males exhibit light spot-induced courtship pursuit without optogenetic priming. Ca(2+) imaging revealed enhanced responses of LPR neurons to visual stimuli in the mutants, suggesting a neural correlate of the light spot-induced courtship behaviour.

References

Mar 14, 1970·Nature·S Crossley, E Zuill
Sep 3, 1996·Proceedings of the National Academy of Sciences of the United States of America·H ItoD Yamamoto
May 15, 2003·Journal of Neurogenetics·Gyunghee LeeJae H Park
Dec 4, 2008·Frontiers in Neuroinformatics·Andrew D Straw
Dec 24, 2008·The Journal of Biological Chemistry·Hongxia WangHiromu Yawo
Feb 14, 2009·PloS One·Dimitrije KrsticMarkus Noll
Oct 16, 2009·Nature·Jean-Christophe BilleterJoel D Levine
Mar 23, 2010·Nature Neuroscience·Elizabeth J RideoutStephen F Goodwin
May 11, 2010·PLoS Biology·Carmen C RobinettBruce S Baker
Jun 8, 2010·Nature Methods·Johannes D SeeligVivek Jayaraman
Feb 15, 2011·Neuron·Anne C von PhilipsbornBarry J Dickson
May 31, 2012·Proceedings of the National Academy of Sciences of the United States of America·Yufeng PanBruce S Baker
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Sep 21, 2013·Nature Reviews. Neuroscience·Daisuke Yamamoto, Masayuki Koganezawa
May 27, 2014·Nature Methods·Daniel E BathAndrew D Straw
Jun 7, 2014·The Journal of Experimental Biology·Sweta AgrawalMichael Dickinson
Dec 1, 1969·Evolution; International Journal of Organic Evolution·Kevin ConnollyDavid Sewell

❮ Previous
Next ❯

Citations

Feb 14, 2016·Current Opinion in Neurobiology·Philip Coen, Mala Murthy
Feb 7, 2016·Current Opinion in Neurobiology·Thomas O Auer, Richard Benton
Aug 19, 2015·Neuron·E Josephine ClowneyVanessa Ruta
May 18, 2016·Current Biology : CB·Masayuki KoganezawaDaisuke Yamamoto
May 18, 2016·Current Opinion in Neurobiology·Eric D Hoopfer
May 18, 2016·Nature Methods·Dhruv GroverRalph J Greenspan
Jun 14, 2016·Neuron·Stephen X ZhangMichael A Crickmore
Oct 19, 2016·Nature Reviews. Neuroscience·David J Anderson
Jan 7, 2017·The Journal of Experimental Biology·Jacob A JezovitJonathan Schneider
Jul 12, 2018·Nature·Laura F SeeholzerVanessa Ruta
Sep 13, 2017·ELife·Esteban J BeckwithGiorgio F Gilestro
Apr 9, 2019·Journal of Neurogenetics·Yuya OnoderaNobuhiro Yamagata
May 31, 2019·Journal of Neurogenetics·Hiromu Tanimoto, Chun-Fang Wu
Dec 27, 2019·Journal of Neurogenetics·Sophie Aimon, Ilona C Grunwald Kadow
Aug 20, 2019·Genes, Brain, and Behavior·Kosei Sato, Daisuke Yamamoto
Feb 7, 2020·Genes·Kosei SatoDaisuke Yamamoto
Sep 14, 2017·Genes, Brain, and Behavior·J LimK-A Han
Aug 16, 2018·Journal of Neurophysiology·Hongxia WangFabrizio Gabbiani
Nov 5, 2019·Frontiers in Behavioral Neuroscience·Kosei SatoDaisuke Yamamoto
Nov 18, 2016·ELife·Hania J PavlouStephen F Goodwin
Feb 1, 2020·Nature Communications·Dhruv GroverRalph J Greenspan
May 30, 2017·Journal of Neurogenetics·Tomohiro HiguchiDaisuke Yamamoto
May 30, 2019·Cell Reports·Osama M AhmedNirao M Shah
Feb 2, 2021·Journal of Neurogenetics·Nicholas RaunJamie M Kramer
Dec 22, 2020·Frontiers in Behavioral Neuroscience·Kosei Sato, Daisuke Yamamoto
Nov 6, 2018·Current Opinion in Physiology·Kenta Asahina
Jul 9, 2021·Nature·Tom Hindmarsh StenVanessa Ruta
Aug 7, 2021·Current Biology : CB·Sherry J CheriyamkunnelCarolina Rezaval
Oct 14, 2021·Cell Reports·Vicki P Losick, Levi G Duhaime
Jun 18, 2021·Science Advances·Stephen X ZhangMichael A Crickmore

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.