PMID: 9192935Jun 1, 1997Paper

Vital capacities in acute and chronic airway obstruction: dependence on flow and volume histories

The European Respiratory Journal
V BrusascoJoseph R Rodarte

Abstract

The aim of this study was to investigate whether measurements of vital capacity (VC) are affected by the direction of the manoeuvre (inspiratory vs expiratory) and by the rate of expiratory flow. The study was performed on 25 individuals with chronic airway obstruction (CAO) and a forced expiratory volume in one second (FEV1) (expressed in standardized residuals (SR)) of -2.0+/-1.4 SD (CAO group), and 10 asthmatic subjects with methacholine (MCh)-induced bronchoconstriction (FEV1 -23+/-1.02 SR) (MCh group). VCs were measured during fast inspiration following both slow (FIVCse) and forced (FIVCfe) expiration from end-tidal inspiration to residual volume (RV), and during slow (EVC) or forced (FVC) expiration from total lung capacity (TLC). In the CAO group, FVC was the smallest volume (3.75+/-1.03 L) and significantly different from the other three estimates of VC; FIVCse (4.03+/-0.91 L) was the largest volume and significantly different from FVC and FIVCfe (3.83+/-0.98 L). In the MCh group, FVC (4.16+/-0.94 L) and EVC (4.19+/-0.89 L) were the largest volumes, although only the difference between FVC and FIVCfe (3.76+/-0.81 L) reached statistical significance. These data suggest that both flow and volume histories contribute to d...Continue Reading

Citations

Sep 26, 2012·Pulmonary Medicine·Nickolaos G KoulourisSofia-Antiopi Gennimata
Nov 18, 2006·American Journal of Respiratory and Critical Care Medicine·Amir SharafkhanehAladin M Boriek
Jun 27, 2003·American Journal of Respiratory and Critical Care Medicine·Franco Laghi, Martin J Tobin
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Jan 23, 2014·Respiratory Physiology & Neurobiology·Wenqiao WangWei Xiao
Sep 16, 2014·Respirology : Official Journal of the Asian Pacific Society of Respirology·Alex Horsley, Salman Siddiqui
Apr 22, 2015·Respiratory Medicine·Andrea RossiMarc Miravitlles
Jul 17, 2013·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Ana Raquel Gonçalves de BarrosNuno Miguel Ferreira Raposo
Dec 21, 2017·Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration·Samad JahandidehDavid L Ennist
May 1, 2019·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Danilo Cortozi Berton, José Alberto Neder
Dec 21, 2019·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Jonathan Jerias FernandezSílvia Carla Sousa Rodrigues
Feb 15, 2017·Multidisciplinary Respiratory Medicine·Mohamed Faisal Lutfi
Jul 8, 2020·BMJ Open Respiratory Research·Karl Peter SylvesterKeith Butterfield
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Oct 16, 2019·American Journal of Respiratory and Critical Care Medicine·Brian L GrahamBruce R Thompson
Mar 13, 2021·The European Respiratory Journal·Graham L HallUNKNOWN contributing GLI Network members

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