Vital capacity inhalation induction with sevoflurane: an alternative to standard intravenous induction for patients undergoing cardiac surgery

Journal of Cardiothoracic and Vascular Anesthesia
G N DjaianiR T Peaston

Abstract

To determine the respiratory and cardiovascular effects of a high concentration vital capacity induction with sevoflurane compared with an intravenous induction with etomidate in patients scheduled for elective coronary artery bypass graft (CABG) surgery. Prospective, randomized, double-blind, controlled clinical trial. Cardiothoracic unit at a university hospital referral center. Twenty-two patients undergoing elective CABG surgery. The study group (group S) received a vital capacity gaseous induction with sevoflurane 8% (n = 12) and the control group (group E) were given etomidate, 0.2 to 0.3 mg/kg (n = 10). Anesthesia was supplemented with fentanyl, 8 microg/kg, and vecuronium, 0.1 mg/kg, in both groups. The speed of induction of anesthesia was comparable between the groups. There was a significant increase in minute ventilation after induction of anesthesia in both groups. This increase was associated with a small reduction in PaCO2. There were no clinically significant changes in pH and PaO(2). The incidence of breath-holding and the need for an oropharyngeal airway were similar between the groups. Both groups had similar reductions in mean arterial pressure and cardiac output during the study period; however, a downward t...Continue Reading

Citations

Jan 7, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Shigeki YamaguchiToshimitsu Kitajima
Jul 13, 2016·Circulation·Robert L PageUNKNOWN American Heart Association Clinical Pharmacology and Heart Failure and Transplantation Committees of the Council on Clinical
May 24, 2006·Anesthesia and Analgesia·Michael C LewisGilbert Chidiac
Apr 28, 2004·European Journal of Anaesthesiology·R Martín-LarrauriC Casimiro
Mar 26, 2019·Paediatric Anaesthesia·Takeo SugitaHirofumi Arisaka
Jan 2, 2021·Journal of Cardiothoracic and Vascular Anesthesia·Yun-Tai YaoJie Ma

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