Vitamin A intake, serum vitamin D and bone mineral density: analysis of the Korea National Health and Nutrition Examination Survey (KNHANES, 2008-2011)

Nutrients
Nam-Seok JooKyung-Jin Yeum

Abstract

The association of high vitamin A intake and low bone mineral density (BMD) is still controversial. To determine the association of dietary vitamin A intake and serum 25-hydroxyvitamin D (25(OH)D) concentration with BMD, a total of 6481 subjects (2907 men and 3574 women) aged ≥50 years from the Korean National Health and Nutrition Examination Survey (2008-2011) were divided into groups according to dietary vitamin A intake (tertiles) and serum 25(OH)D (<50, 50-75, >75 nmol/L), and evaluated for BMD after adjusting for relevant variables. Mean dietary vitamin A intakes were 737 and 600 μg RE (Retinol Equivalents) in men and women, respectively. Total hip and femoral neck BMD in men and lumbar spine BMD in women were both positively correlated with dietary vitamin A intake in subjects with serum 25(OH)D >75 nmol/L. Among men with serum 25(OH)D <50 nmol/L, both the top (mean 1353 μg RE) and bottom (mean 218 μg RE) tertiles of dietary vitamin A intake had lower BMD than the middle group (mean 577 μg RE). In this population, BMD was the highest among men and women with serum 25(OH)D = 50-75 nmol/L and that there were no differences in BMD by vitamin A intake in these vitamin D adequate groups. This cross-sectional study indicates th...Continue Reading

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Citations

Jan 3, 2018·Calcified Tissue International·Cristina Navarro-ValverdeJosé Manuel Quesada-Gómez
Aug 20, 2020·Revista da Escola de Enfermagem da U S P·Kátia Josiany SeghetoGiana Zarbato Longo
May 4, 2018·Current Geriatrics Reports·Jessica WatsonMaria Nieves Garcia-Casal
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Michelle Min Fang YeeSok Kuan Wong
Aug 12, 2021·Ciência & saúde coletiva·Kátia Josiany SeghetoGiana Zarbato Longo

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