Vitamin B12 and folic acid plasma levels after ileocecal and ileal neobladder reconstruction

Urology
M RacioppiE Alcini

Abstract

To compare the plasma levels of vitamin B12 and folic acid following resection of ileocecal or ileal segments used for orthotopic bladder substitution. Hemoglobin, hematocrit, and plasma levels of vitamin B12 and folic acid were measured in 34 patients with ileocecourethrostomy (ICUS) and in 16 patients with ileal reservoir (IR), with a mean follow-up of 59.8 +/- 41.9 months. The results were compared with regard to both the type of operation and the length of time since surgery. The level of folic acid was normal in all patients. The mean level of vitamin B12 in the ICUS group was 413.67 +/- 160.45 ng/mL compared to 257.63 +/- 121.36 for the IR group. This difference was statistically significant. In the IR group, 18.75% of the patients had a level of vitamin B12 below normal. There is a tendency for vitamin B12 levels to fall in patients in whom the ileum is used. Resection of the ileocecal segment including the junction does not alter the level of vitamin B12.

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Citations

Feb 13, 2001·International Journal of Urology : Official Journal of the Japanese Urological Association·M C UygurD Erol
Jul 19, 2002·ANZ Journal of Surgery·Thirumalai GanesanDavid E Neal
Jan 10, 2003·BJU International·E W GerharzC R J Woodhouse
Mar 22, 2000·Current Opinion in Urology·C R Woodhouse
Mar 22, 2000·Current Opinion in Urology·A Stenzl
Mar 26, 2002·The Journal of Urology·Arthur I Sagalowsky, Eugene P Frenkel
Sep 5, 2002·The British Journal of Nutrition·Frédéric GuayJean-Paul Laforest
Sep 9, 2008·The British Journal of Nutrition·Veronika RagallerPeter Lebzien
Jan 5, 2002·Scandinavian Journal of Urology and Nephrology·G OlofssonO Jonsson

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