Vitamin C increases the fecal fat excretion by chitosan in guinea-pigs, thereby reducing body weight gain

Phytotherapy Research : PTR
S C JunH J Suh

Abstract

The aims of this study were to investigate the antiobesity properties of chitosan on its own, as well as in the presence of vitamin C, in vivo. Hartley guinea-pigs were divided into Control (normal diet), F-control (high fat diet), Chitosan (high fat diet with 5.0% chitosan) and Chito-vit C (high fat diet with 5.0% chitosan containing 0.5% vitamin C) groups, respectively. The effects of chitosan, both alone and in the presence of vitamin C, on body weight, total fecal weight, fecal composition and plasma lipid level were studied for 5 weeks. The results of this study indicated that the fat-binding and water-holding capacity of chitosan might decrease body weight by reducing the absorption of cholesterol and fat, subsequently increasing total fecal weight, fecal fat excretion and fecal water excretion. Vitamin C increased the fecal fat excretion by chitosan in guinea-pigs, thereby reducing body weight gain.

References

Dec 1, 1992·Journal of Nutritional Science and Vitaminology·A C ZacourE C Vieira
Jul 31, 1989·Clinica Chimica Acta; International Journal of Clinical Chemistry·N SiliprandiF Di Lisa
Oct 1, 1988·Proceedings of the Society for Experimental Biology and Medicine·C D JenningsJ W Anderson
Dec 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·B FreiB N Ames
Jan 1, 1985·Vitamins and Hormones·M Levine, K Morita
Apr 1, 1980·The American Journal of Clinical Nutrition·M SuganoY Hasegawa
May 1, 1995·Bioscience, Biotechnology, and Biochemistry·K DeuchiE Kobayashi
May 1, 1995·Bioscience, Biotechnology, and Biochemistry·O KanauchiE Kobayashi
Mar 17, 1999·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·L K HanH Okuda
Jun 16, 1999·European Journal of Clinical Nutrition·M H PittlerE Ernst
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
Mar 8, 2003·Clinical and Experimental Medicine·U Mutlu-TürkoğluM Uysal
May 9, 2003·Biological & Pharmaceutical Bulletin·Yoshifumi MurataSusumu Kawashima
May 29, 2003·European Journal of Clinical Nutrition·H Bokura, S Kobayashi
Aug 1, 1959·Canadian Journal of Biochemistry and Physiology·E G BLIGH, W J DYER
Nov 18, 2003·Acta Diabetologica·E RedaM Calvani
Jan 10, 2004·The Journal of Pharmacy and Pharmacology·María José Alonso, Alejandro Sánchez
Feb 3, 2004·Journal of Chromatography. a·Guanghou Shui, Lai Peng Leong
Mar 31, 2004·The American Journal of Clinical Nutrition·Max H Pittler, Edzard Ernst
Aug 18, 2004·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·C Ni MhurchuA Rodgers
Dec 16, 2004·The Journal of Clinical Investigation·Shigetada FurukawaIichiro Shimomura
Jan 19, 2005·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·C Ni MhurchuA Rodgers
Mar 8, 2005·Free Radical Biology & Medicine·A F SoaresA Géloën
Jun 3, 2005·Journal of the American College of Nutrition·Carol S Johnston
Sep 13, 2005·Biomacromolecules·Hilda Parra-BarrazaMiguel A Valdez
Oct 29, 2005·Journal of Pediatric Gastroenterology and Nutrition·Anthony F Philipps
Feb 3, 2006·The Journal of Pharmacy and Pharmacology·Maho Sumiyoshi, Yoshiyuki Kimura
Dec 2, 2006·Pharmazie in unserer Zeit·Ralf Goebel, Martin Schulz
May 8, 2007·European Journal of Pharmacology·Giampietro BondiolottiUmberto Cornelli
Jan 17, 2008·The Laryngoscope·Ulf-Rüdiger HeinrichKai Helling
Jul 23, 2008·The Cochrane Database of Systematic Reviews·Andrew B JullAnthony Rodgers

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International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition
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