Vitamin D -- the sun hormone. Life in environmental mismatch

Biochemistry. Biokhimii︠a︡
H Göring, S Koshuchowa

Abstract

While some representatives of the animal kingdom were improving their biological mechanisms and properties for adapting to ever-changing life conditions, the genus Homo was developing backward: human individuals were losing their adaptation to life areas conquered earlier. Losing step-by-step their useful traits including the body hair cover, the primitive genus Homo retained his viability only under very favorable conditions of the equatorial Africa. Protection from UV radiation danger was provided only by pigmentation of skin, hair, and eyes. However, "impoverished" individuals of this genus gained the ability to walk upright. Their hands became free from participation in movement and became fine tools for producing useful instruments, from the stone knife to the computer. The major consequence of upright movement and hand development became the powerful development of the brain. A modern human, Homo sapiens, appeared capable of conquering very diverse new habitats. The human's expansion on the Earth occurred somewhat limited by his dependence on vitamin D. His expansion into new areas with lower Sun activity was partially associated with the loss of skin pigmentation. But there is an open question, whether under these new co...Continue Reading

References

Jan 6, 1975·Biochemical and Biophysical Research Communications·R H WassermanL P Krook
Dec 1, 1971·The Journal of Clinical Endocrinology and Metabolism·J G Haddad, K J Chyu
May 7, 1974·Biochemical and Biophysical Research Communications·A UribeH F DeLuca
Sep 1, 1973·The Journal of Nutrition·H A Schneider
Oct 15, 1973·Experientia·E Havinga
Apr 30, 1983·Lancet·D R Fraser
Jan 1, 1980·Advances in Experimental Medicine and Biology·O S BetterC Chaimovitz
Apr 11, 1995·Proceedings of the National Academy of Sciences of the United States of America·M F HolickM Allen
Mar 1, 1995·The American Journal of Clinical Nutrition·M F Holick
May 1, 1999·The Journal of Nutrition·K J Carpenter, L Zhao
Sep 22, 1999·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·S M OttL Newell-Morris
Dec 29, 2000·Nature·M IngmanU Gyllensten
Aug 9, 2001·Australian Veterinary Journal·M E DallorsoA Márquez
Dec 1, 2001·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·H F Deluca, M T Cantorna
Dec 7, 2002·Toxicon : Official Journal of the International Society on Toxinology·J R B Mello
Jan 10, 2003·Journal of Cellular Biochemistry·Michael F Holick
Apr 4, 2003·The Journal of Nutrition·Robert P Heaney
Feb 27, 2004·The American Journal of Clinical Nutrition·Michael F Holick
Jul 1, 2004·The Journal of Steroid Biochemistry and Molecular Biology·J L DavideauA Berdal
Dec 9, 2004·The American Journal of Clinical Nutrition·Pamela WeisbergMary E Cogswell
Dec 9, 2004·The American Journal of Clinical Nutrition·Mona S CalvoCurtis N Barton
Mar 28, 2006·Progress in Biophysics and Molecular Biology·Margherita T Cantorna
Aug 4, 2006·The Journal of Clinical Investigation·Michael F Holick
Sep 9, 2006·Epidemiology and Infection·J J CannellE Giovannucci
Nov 3, 2006·Pediatrics·Helen M PappaRichard J Grand
Jan 27, 2007·Archives of Biochemistry and Biophysics·Tai C ChenMichael F Holick
Mar 14, 2007·Epidemiology and Infection·John F Aloia, Melissa Li-Ng
Jun 7, 2007·Pediatric Rheumatology Online Journal·Yosef Uziel, Philip J Hashkes
Jul 20, 2007·The New England Journal of Medicine·Michael F Holick
Jan 5, 2008·International Journal of Dermatology·William TingHobart W Walling
May 27, 2008·Metabolism: Clinical and Experimental·Laura D CarboneKarl T Weber
Sep 30, 2008·Journal of Foot and Ankle Research·Angela M Evans
Mar 9, 2010·Nature Immunology·Marina Rode von EssenCarsten Geisler
Mar 12, 2010·The American Journal of Clinical Nutrition·Mitsuyoshi UrashimaHiroyuki Ida
Mar 23, 2011·Infection and Immunity·Laura McMahonGill Diamond
Sep 17, 2011·Journal of Agricultural and Food Chemistry·Rie Bak JäpeltJette Jakobsen
Jan 25, 2012·Nature Reviews. Rheumatology·John McBeth, Matthew R Mulvey
Feb 9, 2012·Rheumatology International·Shereem Mohamed OlamaGalal Elhawary
Mar 1, 2012·The Plant Cell·Teresa B FitzpatrickAlisdair R Fernie
Mar 15, 2012·Steroids·Martin Blomberg Jensen, Steen Dissing
Mar 24, 2012·The Journal of Clinical Endocrinology and Metabolism·Michael F HolickConnie M Weaver

❮ Previous
Next ❯

Citations

Jun 14, 2015·Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición·Raif M BotrosLaila M Hendawy
Mar 6, 2017·Biochemistry. Biokhimii︠a︡·H Göring, S Koshuchowa
Jul 28, 2020·Critical Reviews in Food Science and Nutrition·Valentina StacchiottiFrancesco Galli
Dec 29, 2020·Frontiers in Nutrition·José João NameCarolina Parga Martins Pereira

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Archives of Environmental Health
H P Wassermann
JAMA : the Journal of the American Medical Association
June K Robinson
European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)
A McKinlayR Greinert
© 2022 Meta ULC. All rights reserved