Vitamin D and gestational diabetes: an update

Current Opinion in Clinical Nutrition and Metabolic Care
Jan S JoergensenMaria R Torloni


Vitamin D status (which is involved in glucose homeostasis) is related to gestational diabetes mellitus (GDM). GDM is characterized by increased resistance to and impaired secretion of insulin and results in higher risk of adverse pregnancy outcomes including operative delivery, macrosomia, shoulder dystocia and neonatal hypoglycemia. Women with GDM and their babies are at increased risk for developing type II diabetes. International definitions of vitamin D deficiency and normality are inconsistent. Vitamin D deficiency is common in pregnant women particularly those with poor diets and who have dark skins living in temperate climes with lack of exposure to sunlight. Few interventional studies indicate that supplementation optimizes maternal vitamin D status or improves maternal glucose metabolism. Observational studies about maternal vitamin D status and risk of GDM are conflicting. This could be because of measurement of vitamin D or differences in population characteristics such as ethnicity, geographic location, gestational age at sampling and diagnostic criteria for GDM. Good-quality randomized controlled trials are required to determine whether vitamin D supplementation decreases the risk of GDM or improves glucose tolera...Continue Reading


Dec 25, 2002·The American Journal of Clinical Nutrition·Robert P HeaneyM Janet Barger-Lux
Mar 29, 2007·The Journal of Clinical Endocrinology and Metabolism·Anastassios G PittasBess Dawson-Hughes
Oct 23, 2009·American Journal of Obstetrics and Gynecology·Megan L MulliganCarlos Bernal-Mizrachi
Jun 1, 2010·American Journal of Obstetrics and Gynecology·Donald R CoustanInternational Association of Diabetes and Pregnancy Study Groups
Jan 17, 2012·Clinical Chemistry·Annemieke C HeijboerMadelon M Buijs
Jun 26, 2012·European Journal of Internal Medicine·Y H M PoelS Simsek
Sep 15, 2012·Acta Obstetricia Et Gynecologica Scandinavica·H T ChristesenJ S Jørgensen
Jan 15, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Shu-Qin WeiWilliam D Fraser
Jan 15, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Carol L WagnerBruce W Hollis
Jan 29, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sedigheh SoheilykhahAhmad Shojaoddiny-Ardekani
Apr 6, 2013·The Journal of Clinical Endocrinology and Metabolism·Adekunle DawoduBruce W Hollis
May 15, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·L E TomediL M Bodnar
Jul 12, 2013·International Journal of Women's Health·Adekunle Dawodu, Henry Akinbi
Aug 2, 2013·Evidence-based Medicine·Adrian R Martineau, Khalid Khan
Aug 21, 2013·American Journal of Obstetrics and Gynecology·Geum Joon ChoHai-Joong Kim
Nov 28, 2013·Current Diabetes Reports·Heather H Burris, Carlos A Camargo


Sep 27, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Serpil AydogmusGülcan Sağlam
Feb 6, 2016·Paediatric and Perinatal Epidemiology·Linda DoddsYves Giguère
Aug 26, 2016·Critical Reviews in Food Science and Nutrition·Shreya AgarwalDevendra K Agrawal
Apr 11, 2018·BMC Pregnancy and Childbirth·Abdulrahman Al-AjlanNasser M Al-Daghri
Feb 5, 2016·Nutrition and Metabolic Insights·Saranya PalaniswamySylvain Sebert
Dec 6, 2019·Indian Journal of Endocrinology and Metabolism·Prashant TripathiKirti Amresh Gautam
Dec 19, 2019·Reproductive Biology and Endocrinology : RB&E·Beibei DongLing Li
Sep 19, 2019·Journal of Complementary & Integrative Medicine·Federica Di GuardoGianluca Rizzo
Aug 27, 2019·Frontiers in Nutrition·Pratibha DwarkanathAnura V Kurpad
Sep 29, 2017·Journal of Bone Metabolism·Hyun Koo Yoon

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Related Papers

The Cochrane Database of Systematic Reviews
Shanshan HanCaroline A Crowther
The Australian & New Zealand Journal of Obstetrics & Gynaecology
Chaturica AthukoralaAustrailian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group
© 2021 Meta ULC. All rights reserved