Vitamin D and gestational diabetes: an update

Current Opinion in Clinical Nutrition and Metabolic Care
Jan S JoergensenMaria R Torloni

Abstract

Vitamin D status (which is involved in glucose homeostasis) is related to gestational diabetes mellitus (GDM). GDM is characterized by increased resistance to and impaired secretion of insulin and results in higher risk of adverse pregnancy outcomes including operative delivery, macrosomia, shoulder dystocia and neonatal hypoglycemia. Women with GDM and their babies are at increased risk for developing type II diabetes. International definitions of vitamin D deficiency and normality are inconsistent. Vitamin D deficiency is common in pregnant women particularly those with poor diets and who have dark skins living in temperate climes with lack of exposure to sunlight. Few interventional studies indicate that supplementation optimizes maternal vitamin D status or improves maternal glucose metabolism. Observational studies about maternal vitamin D status and risk of GDM are conflicting. This could be because of measurement of vitamin D or differences in population characteristics such as ethnicity, geographic location, gestational age at sampling and diagnostic criteria for GDM. Good-quality randomized controlled trials are required to determine whether vitamin D supplementation decreases the risk of GDM or improves glucose tolera...Continue Reading

References

Dec 25, 2002·The American Journal of Clinical Nutrition·Robert P HeaneyM Janet Barger-Lux
Mar 29, 2007·The Journal of Clinical Endocrinology and Metabolism·Anastassios G PittasBess Dawson-Hughes
Oct 23, 2009·American Journal of Obstetrics and Gynecology·Megan L MulliganCarlos Bernal-Mizrachi
Jun 1, 2010·American Journal of Obstetrics and Gynecology·Donald R CoustanInternational Association of Diabetes and Pregnancy Study Groups
Jan 17, 2012·Clinical Chemistry·Annemieke C HeijboerMadelon M Buijs
Jun 26, 2012·European Journal of Internal Medicine·Y H M PoelS Simsek
Sep 15, 2012·Acta Obstetricia Et Gynecologica Scandinavica·H T ChristesenJ S Jørgensen
Jan 15, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Shu-Qin WeiWilliam D Fraser
Jan 15, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Carol L WagnerBruce W Hollis
Jan 29, 2013·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Sedigheh SoheilykhahAhmad Shojaoddiny-Ardekani
Apr 6, 2013·The Journal of Clinical Endocrinology and Metabolism·Adekunle DawoduBruce W Hollis
May 15, 2013·Diabetic Medicine : a Journal of the British Diabetic Association·L E TomediL M Bodnar
Jul 12, 2013·International Journal of Women's Health·Adekunle Dawodu, Henry Akinbi
Aug 2, 2013·Evidence-based Medicine·Adrian R Martineau, Khalid Khan
Aug 21, 2013·American Journal of Obstetrics and Gynecology·Geum Joon ChoHai-Joong Kim
Nov 28, 2013·Current Diabetes Reports·Heather H Burris, Carlos A Camargo

Citations

Sep 27, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Serpil AydogmusGülcan Sağlam
Feb 6, 2016·Paediatric and Perinatal Epidemiology·Linda DoddsYves Giguère
Aug 26, 2016·Critical Reviews in Food Science and Nutrition·Shreya AgarwalDevendra K Agrawal
Apr 11, 2018·BMC Pregnancy and Childbirth·Abdulrahman Al-AjlanNasser M Al-Daghri
Feb 5, 2016·Nutrition and Metabolic Insights·Saranya PalaniswamySylvain Sebert
Dec 6, 2019·Indian Journal of Endocrinology and Metabolism·Prashant TripathiKirti Amresh Gautam
Dec 19, 2019·Reproductive Biology and Endocrinology : RB&E·Beibei DongLing Li
Sep 19, 2019·Journal of Complementary & Integrative Medicine·Federica Di GuardoGianluca Rizzo
Aug 27, 2019·Frontiers in Nutrition·Pratibha DwarkanathAnura V Kurpad
Sep 29, 2017·Journal of Bone Metabolism·Hyun Koo Yoon

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